6,7-Dehydro Prednisolone 21-Acetate

Base Information

Chemical Name:6,7-Dehydro Prednisolone 21-Acetate
CAS No.:2427-45-4
Molecular Formula:C₂₃H₂₈O₆
Molecular Weight:400.472
Hs Code.:
UNII:SK3PYA658V
DSSTox Substance ID:DTXSID60595068
Wikidata:Q82490006
Mol file:2427-45-4.mol

Synonyms:6,7-Dehydro Prednisolone 21-Acetate;2427-45-4;[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;SK3PYA658V;SCHEMBL11315001;DTXSID60595068;(11beta)-11,17-Dihydroxy-3,20-dioxopregna-1,4,6-trien-21-yl acetate;Pregna-1,4,6-triene-3,20-dione, 11beta,17,21-trihydroxy-, 21-acetate;Pregna-1,4,6-triene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11beta)-;2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate

Suppliers and Price of 6,7-Dehydro Prednisolone 21-Acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6,7-DehydroPrednisolone21-Acetate
5mg
$ 175.00

TRC
6,7-DehydroPrednisolone21-Acetate
10mg
$ 315.00

TRC
6,7-DehydroPrednisolone21-Acetate
25mg
$ 750.00

Biosynth Carbosynth
6,7-Dehydro prednisolone 21-acetate
25 mg
$ 920.00

Biosynth Carbosynth
6,7-Dehydro prednisolone 21-acetate
10 mg
$ 460.00

Biosynth Carbosynth
6,7-Dehydro prednisolone 21-acetate
5 mg
$ 280.00

Biosynth Carbosynth
6,7-Dehydro prednisolone 21-acetate
2 mg
$ 180.00

Biosynth Carbosynth
6,7-Dehydro prednisolone 21-acetate
1 mg
$ 100.00

Total 8 raw suppliers

Chemical Property of 6,7-Dehydro Prednisolone 21-Acetate

Chemical Property:

Melting Point:207-210.2 °C
Boiling Point:597.5±50.0 °C(Predicted)
PKA:12.38±0.70(Predicted)
PSA：100.90000
Density:1.30±0.1 g/cm3(Predicted)
LogP:1.90440
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:400.18858861
Heavy Atom Count:29
Complexity:869

Purity/Quality:

99% ^*data from raw suppliers

6,7-DehydroPrednisolone21-Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2C=CC4=CC(=O)C=CC34C)O)C)O
Isomeric SMILES:CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2C=CC4=CC(=O)C=C[C@]34C)O)C)O
Uses Protected Prednisone metabolite.

Technology Process of 6,7-Dehydro Prednisolone 21-Acetate

There total 4 articles about 6,7-Dehydro Prednisolone 21-Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-03-3
hydrocortisone acetate

: 2427-45-4
21-acetoxy-11β,17α-dihydroxypregna-1,4,6-triene-3,20-dione

Guidance literature:: With chloranil;
DOI:10.1021/ja01562a058

Reference yield:

: 21940-45-4
6,7-dehydrocortisol 21-acetate

: 2427-45-4
21-acetoxy-11β,17α-dihydroxypregna-1,4,6-triene-3,20-dione

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; Yield given; Heating;

Reference yield:

: 2427-45-4
11β.17α-Dihydroxy-21-acetoxy-3.20-dioxo-pregnatrien-(1.4.6)

Guidance literature:: neben gleichen Mengen 11β.17α-Dihydroxy-21-acetoxy-pregnadien-(4.6)-dion-(3.20) aus Cortisol-acetat und 2.6-Dichlor-p-benzochinon in sied. sek.-Amylalkohol <2 Stdn., N2>;
DOI:10.1021/ja01501a045