2-Methyloxazole-4-carbothioamide

Base Information

• Chemical Name: 2-Methyloxazole-4-carbothioamide
• CAS No.: 90980-10-2
• Molecular Formula: C₅H₆N₂OS
• Molecular Weight: 142.181
• Hs Code.: 2924210090
• Mol file: 90980-10-2.mol

Synonyms:2-Methyloxazole-4-carbothioamide

Chemical Property of 2-Methyloxazole-4-carbothioamide

Chemical Property:

• PSA: 88.68000
• LogP: 1.33790

Purity/Quality:

97% ^*data from raw suppliers

2-Methyloxazole-4-carbothioamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyloxazole-4-carbothioamide

There total 4 articles about 2-Methyloxazole-4-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-4-carbethoxy-1,3-oxazole (10200-43-8) → 2-methyl-oxazole-4-carbothioic acid amide (90980-10-2)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. NH₃

2: POCl₃

3: H₂S, Et₃N / ethanol

With ammonium hydroxide; hydrogen sulfide; triethylamine; trichlorophosphate; In ethanol;

Reference yield:

2-Methyloxazole-4-carboxamide (100959-91-9) → 2-methyl-oxazole-4-carbothioic acid amide (90980-10-2)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: H₂S, Et₃N / ethanol

With hydrogen sulfide; triethylamine; trichlorophosphate; In ethanol;

Reference yield:

2-methyl-4-oxazolecarbonitrile (89282-09-7) → 2-methyl-oxazole-4-carbothioic acid amide (90980-10-2)

Guidance literature:

With hydrogen sulfide; triethylamine; In ethanol;

DOI:10.1002/hlca.19600430610

upstream raw materials:

2-methyl-4-oxazolecarbonitrile

2-methyl-4-carbethoxy-1,3-oxazole

N-cyanomethyl-acetimidic acid ethyl ester

2-Methyloxazole-4-carboxamide

Downstream raw materials:

2-methyl-4-(4-phenyl-thiazol-2-yl)-oxazole

2-methyl-4-(4-p-tolyl-thiazol-2-yl)-oxazole

4-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-methyl-oxazole

2-methyl-4-[4-(4-nitro-phenyl)-thiazol-2-yl]-oxazole