3-amino-5,6-diphenyl-2-Pyrazinecarboxylic acid

Base Information

• Chemical Name: 3-amino-5,6-diphenyl-2-Pyrazinecarboxylic acid
• CAS No.: 854699-15-3
• Molecular Formula: C₁₇H₁₃N₃O₂
• Molecular Weight: 0
• Mol file: 854699-15-3.mol

Synonyms:3-amino-5,6-diphenyl-2-Pyrazinecarboxylic acid

Chemical Property of 3-amino-5,6-diphenyl-2-Pyrazinecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-amino-5,6-diphenyl-2-Pyrazinecarboxylic acid

There total 2 articles about 3-amino-5,6-diphenyl-2-Pyrazinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,7-diphenylpteridine-2,4(1H,3H)-dione (14892-98-9) → 3-amino-5,6-diphenyl-pyrazine-2-carboxylic acid (854699-15-3)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01221a032

Reference yield:

benzil (134-81-6) → 3-amino-5,6-diphenyl-pyrazine-2-carboxylic acid (854699-15-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous ethanol NH₃

2: aq. NaOH solution

With sodium hydroxide; ammonia;

DOI:10.1021/ja01221a032

Reference yield:

2-aminopyridine (504-29-0) + 3-amino-5,6-diphenyl-pyrazine-2-carboxylic acid (854699-15-3) → 3-amino-5,6-diphenyl-N-pyridin-2-yl-pyrazine-2-carboxamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; at 20 ℃; for 24h;

upstream raw materials:

6,7-diphenylpteridine-2,4(1H,3H)-dione

benzil

Downstream raw materials:

2-amino-5,6-diphenylpyrazine