2-Methylbutanedioic acid dibutyl ester

Base Information

• Chemical Name: 2-Methylbutanedioic acid dibutyl ester
• CAS No.: 18447-89-7
• Molecular Formula: C13H24O4
• Molecular Weight: 244.331
• Mol file: 18447-89-7.mol

Synonyms:2-Methylbutanedioic acid dibutyl ester;2-Methylsuccinic acid dibutyl ester

Chemical Property of 2-Methylbutanedioic acid dibutyl ester

Chemical Property:

• Melting Point: -34.4 °C
• PSA: 52.60000
• LogP: 2.69920

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methylbutanedioic acid dibutyl ester

There total 3 articles about 2-Methylbutanedioic acid dibutyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Allyl ether (557-40-4) + carbon monoxide (201230-82-2) + butan-1-ol (71-36-3) → methyl-succinic acid dibutyl ester (18447-89-7) + Pentanedioic acid dibutyl ester (6624-57-3)

Guidance literature:

With hydrogenchloride; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In diethyl ether; toluene; at 110 ℃; for 24h; under 30003 Torr; Overall yield = 93 %Chromat.; Inert atmosphere; Autoclave;

Reference yield:

carbon monoxide (201230-82-2) + allyl alcohol (107-18-6) + butan-1-ol (71-36-3) → methyl-succinic acid dibutyl ester (18447-89-7) + Pentanedioic acid dibutyl ester (6624-57-3)

Guidance literature:

With hydrogenchloride; palladium(II) acetylacetonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In diethyl ether; toluene; at 105 ℃; for 24h; under 30003 Torr; Reagent/catalyst; Temperature; Solvent; Pressure; Concentration; Overall yield = 77 %; Inert atmosphere; Autoclave;

Reference yield:

allyl n-butyl ether (3739-64-8) + carbon monoxide (201230-82-2) + butan-1-ol (71-36-3) → methyl-succinic acid dibutyl ester (18447-89-7) + Pentanedioic acid dibutyl ester (6624-57-3)

Guidance literature:

With hydrogenchloride; palladium(II) trifluoroacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In diethyl ether; toluene; at 110 ℃; for 24h; under 30003 Torr; Reagent/catalyst; Solvent; Concentration; Overall yield = 94 %Chromat.; Catalytic behavior; Inert atmosphere; Autoclave;

upstream raw materials:

allyl n-butyl ether

carbon monoxide

butan-1-ol

Allyl ether

Refernces

• 1、 -. "PROCESS FOR DOUBLE CARBONYLATION OF ALLYL ALCOHOLS TO CORRESPONDING DIESTERS". Paragraph 0064; 0069; 0070; 0075-0182. . Retrieved 2017/07/14.