PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl-

Base Information

Chemical Name:PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl-
CAS No.:885609-84-7
Molecular Formula:C11H13BrFNO
Molecular Weight:274.133
Hs Code.:
Mol file:885609-84-7.mol

Synonyms:PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl-;N-(2-broMo-5-fluorophenyl)pivalaMide;N-(2-BroMo-5-fluoro-phenyl)-2,2-diMethyl-propionaMide

Suppliers and Price of PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(2-Bromo-5-fluorophenyl)pivalamide 95+%
5g
$ 549.00

Chemcia Scientific
N-(2-Bromo-5-fluoro-phenyl)-2,2-dimethyl-propionamide ＞97%
1 G
$ 225.00

American Custom Chemicals Corporation
N-(2-BROMO-5-FLUOROPHENYL)PIVALAMIDE 95.00%
5MG
$ 503.05

Total 11 raw suppliers

Chemical Property of PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl-

Chemical Property:

PSA：32.59000
LogP:4.22230
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N-(2-Bromo-5-fluorophenyl)pivalamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl-

There total 1 articles about PropanaMide, N-(2-broMo-5-fluorophenyl)-2,2-diMethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1003-99-2
2-bromo-5-fluoroaniline

: 3282-30-2
pivaloyl chloride

: 885609-84-7
N-(2-bromo-5-fluorophenyl)pivalamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 885609-84-7
N-(2-bromo-5-fluorophenyl)pivalamide

: 73183-34-3
bis(pinacol)diborane

: 1202805-45-5
N-[5-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,2-dimethylpropanamide

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 25 - 105 ℃; Inert atmosphere;

Reference yield:

: 885609-84-7
N-(2-bromo-5-fluorophenyl)pivalamide

: 1202805-94-4
N-[4-bromo-5-fluoro-2-(pyridin-2-yl)phenyl]-2,2-dimethylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 2 h / 100 °C

2: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; acetonitrile / 8 h / 80 °C / Inert atmosphere

3: N-Bromosuccinimide; acetic acid / 1 h / 0 - 50 °C

With N-Bromosuccinimide; potassium acetate; potassium carbonate; acetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; water; acetonitrile;