2-Furanethanol, 5-Methyl-

Base Information

• Chemical Name: 2-Furanethanol, 5-Methyl-
• CAS No.: 35942-94-0
• Molecular Formula: C7H10O2
• Molecular Weight: 126.1531
• Mol file: 35942-94-0.mol

Synonyms:2-Furanethanol, 5-Methyl-;2-(5-methylfuran-2-yl)ethanol;5-methyl-2-Furanethanol

Chemical Property of 2-Furanethanol, 5-Methyl-

Chemical Property:

• PSA: 33.37000
• LogP: 1.12280
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

2-(5-Methylfuran-2-yl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-(5-Methylfuran-2-yl)ethanol is used in the synthetic preparation of selective androgen receptor modulators, which exhibits antagonist activity in some types of hormone-dependent tumors.

Technology Process of 2-Furanethanol, 5-Methyl-

There total 7 articles about 2-Furanethanol, 5-Methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ 2-(5-methylfuran-2-yl)ethanol (35942-94-0)

Guidance literature:

Reference yield: 90.0%

ethyl 2-(5-methylfuran-2-yl)acetate (53906-90-4) → 2-(5-methylfuran-2-yl)ethanol (35942-94-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c2gc16397g

Reference yield: 72.0%

oxirane (75-21-8,99932-75-9) + 2-methylfuran (534-22-5) → 2-(5-methylfuran-2-yl)ethanol (35942-94-0)

Guidance literature:

2-methylfuran; With n-butyllithium; In tetrahydrofuran; hexanes; at 0 - 20 ℃; for 4h;

oxirane; In tetrahydrofuran; hexanes; at 20 ℃; for 16h;

upstream raw materials:

2,5-dimethylfuran

formaldehyd

oxirane

2-methylfuran

Downstream raw materials:

C₇H₈O₂

2-Methyl-5-[2-[4-(trifluoromethyl)phenoxy]ethyl]furan

5-Methyl-2-furanethanol 4-methylbenzenesulfonate