Ethyl 3-chloro-4-forMylbenzoate

Base Information

• Chemical Name: Ethyl 3-chloro-4-forMylbenzoate
• CAS No.: 908248-02-2
• Molecular Formula: C10H9ClO3
• Molecular Weight: 212.62966
• Hs Code.: 2918300090
• Mol file: 908248-02-2.mol

Synonyms:Ethyl 3-chloro-4-forMylbenzoate

Chemical Property of Ethyl 3-chloro-4-forMylbenzoate

Chemical Property:

• Boiling Point: 310.5±27.0 °C(Predicted)
• PSA: 43.37000
• Density: 1.315±0.06 g/cm3(Predicted)
• LogP: 2.32920

Purity/Quality:

99% ^*data from raw suppliers

Methyl2-Chloro-4-formylbenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 3-chloro-4-forMylbenzoate

There total 3 articles about Ethyl 3-chloro-4-forMylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

4-bromo-2-chlorobenzoic acid methyl ester (185312-82-7) + sodium formate (141-53-7) → methyl 2-chloro-4-formylbenzoate (908248-02-2)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; carbon monoxide; In N,N-dimethyl-formamide; at 110 ℃; for 2h;

DOI:10.1021/jm401695d

Reference yield:

4-bromo-2-chlorobenzoic acid methyl ester (185312-82-7) + carbon monoxide (201230-82-2) + sodium formate (141-53-7) → methyl 2-chloro-4-formylbenzoate (908248-02-2)

Guidance literature:

bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 110 ℃; for 2h;

Reference yield:

4-Bromo-2-chloro-benzoic Acid (59748-90-2) → methyl 2-chloro-4-formylbenzoate (908248-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; tetrahydrofuran / 1 h / 0 - 20 °C

2: bis-triphenylphosphine-palladium(II) chloride; carbon monoxide / N,N-dimethyl-formamide / 2 h / 110 °C

With bis-triphenylphosphine-palladium(II) chloride; carbon monoxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm401695d

upstream raw materials:

4-bromo-2-chlorobenzoic acid methyl ester

carbon monoxide

sodium formate

4-Bromo-2-chloro-benzoic Acid

Downstream raw materials:

(E)-2-chloro-4-(3,3,3-trifluoroprop-1-enyl)benzoic acid

ethyl 2-chloro-4-(2-oxo-5,6-diphenyl-1,2,3,4-tetrahydropyrimidin-4-yl)benzoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 908248-02-2 Ethyl 3-chloro-4-forMylbenzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send