DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Base Information

Chemical Name:DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
CAS No.:145618-64-0
Molecular Formula:C₁₂H₂₃NO₄
Molecular Weight:245.319
Hs Code.:
Mol file:145618-64-0.mol

Synonyms:DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Suppliers and Price of DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Chemical Property:

PSA：64.63000
LogP:2.63380

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

There total 5 articles about DL-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 811-49-4
ethyllithium

: 87974-88-7
4-iodo-2-tert-butoxycarbonylamino-butyric acid methyl ester

: 145618-64-0
methyl 2-(tert-butoxycarbonylamino) hexanoate

Guidance literature:: With copper(l) iodide; In diethyl ether; at -60 ℃; for 3h;
DOI:10.1016/S0040-4039(00)94517-9

Reference yield: 6.0%

: 2417-93-8
propyllithium

: 69961-11-1
2-tert-butoxycarbonylamino-3-(toluene-4-sulfonyloxy)-propionic acid methyl ester

: 55477-80-0
methyl 2-[(tert-butoxycarbonyl)amino]acrylate

: 145618-64-0
methyl 2-(tert-butoxycarbonylamino) hexanoate

Guidance literature:: With copper(l) iodide; In diethyl ether; at -60 ℃; for 3h;
DOI:10.1016/S0040-4039(00)94517-9

Reference yield:

: 811-49-4
ethyllithium

: 76969-87-4,127305-42-4
tert-Butyloxycarbonyl-L-α-amino-γ-bromobutyric acid methyl ester

: 87974-77-4,116611-59-7,145618-64-0
2-tert-Butoxycarbonylamino-hexanoic acid methyl ester

Guidance literature:: With copper(l) iodide; Yield given. Multistep reaction; 1.) THF, -60 deg C, 30 min. 2.) -10 deg C, 7 h. Var_.: add of dibutylsulfide;
DOI:10.1016/S0040-4039(01)80218-5