D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Base Information

Chemical Name:D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
CAS No.:116611-59-7
Molecular Formula:C₁₂H₂₃NO₄
Molecular Weight:245.319
Hs Code.:
Mol file:116611-59-7.mol

Synonyms:D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Suppliers and Price of D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Chemical Property:

PSA：64.63000
LogP:2.63380

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

There total 19 articles about D-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 145618-64-0
methyl 2-(tert-butoxycarbonylamino) hexanoate

: 6404-28-0
Boc-Nle-OH

: 116611-59-7
D-N-Boc-nor-leucine methyl ester

Guidance literature:: With Bacillus licheniformis; In water; at 37 ℃; for 15h; pH=8.0;
DOI:10.1016/j.tetasy.2006.07.012

Reference yield: 10.0%

: 93267-04-0,170848-34-7,889670-02-4
N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester

: 55477-80-0
methyl 2-[(tert-butoxycarbonyl)amino]acrylate

: 116611-59-7
D-N-Boc-nor-leucine methyl ester

: 87974-77-4
methyl (2S)-2-tert-butoxycarbonylaminohexanoate

Guidance literature:: In diethyl ether; at -60 ℃; for 3h; Yield given. Title compound not separated from byproducts;
DOI:10.1016/S0040-4039(01)81283-1

Reference yield: 10.0%

: 93267-04-0,170848-34-7,889670-02-4
N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester

: 55477-80-0
methyl 2-[(tert-butoxycarbonyl)amino]acrylate

: 116611-59-7
D-N-Boc-nor-leucine methyl ester

: 87974-77-4
methyl (2S)-2-tert-butoxycarbonylaminohexanoate

Guidance literature:: With di-n-propylcopperlithium; In diethyl ether; at -60 ℃; for 3h; reaction of various organocuprates with halogeno and tosyl derivatives of L-serine with β-elimination, racemisation;
DOI:10.1016/S0040-4020(01)96546-9