Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI)

Base Information

Chemical Name:Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI)
CAS No.:337530-34-4
Molecular Formula:C11H16N2
Molecular Weight:176.261
Hs Code.:
Mol file:337530-34-4.mol

Synonyms:Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI);(3S)-3-METHYL-1-PHENYLPIPERAZINE

Suppliers and Price of Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI)

Chemical Property:

PSA：15.27000
LogP:1.87850

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI)

There total 5 articles about Piperazine, 3-methyl-1-phenyl-, (3S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (S)-tert-butyl-2-methyl-4-phenylpiperazine-1-carboxylate

: 337530-34-4
(3S)-3-methyl-1-phenylpiperazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h; Reagent/catalyst; Solvent;

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 74879-18-8
(S)-2-methylpiperazine

: 337530-34-4
(3S)-3-methyl-1-phenylpiperazine

Guidance literature:: bromobenzene; (S)-2-methylpiperazine; With sodium t-butanolate; In toluene; at 100 ℃; for 4h;

With sodium hydrogencarbonate; In water; toluene; at 20 ℃;

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 169447-70-5
(S)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester

: 337530-34-4
(3S)-3-methyl-1-phenylpiperazine

Guidance literature:: bromobenzene; (S)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester; With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In toluene; at 100 ℃; for 18h; Inert atmosphere;

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;