(S)-(+)-2-Methylpiperazine

Base Information

Chemical Name:(S)-(+)-2-Methylpiperazine
CAS No.:74879-18-8
Molecular Formula:C5H12N2
Molecular Weight:100.164
Hs Code.:29335990
European Community (EC) Number:627-535-8
UNII:C5VI3S1YC0
Nikkaji Number:J872.074F
Wikidata:Q27275227
Mol file:74879-18-8.mol

Synonyms:2(S)-methyl piperazine;2-methyl piperazine;2-methylpiperazine

Suppliers and Price of (S)-(+)-2-Methylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S)-2-Methylpiperazine
250g
$ 605.00

TRC
(2S)-2-Methylpiperazine
5g
$ 60.00

TRC
(2S)-2-Methylpiperazine
25g
$ 100.00

TCI Chemical
(S)-(+)-2-Methylpiperazine >97.0%(T)
1g
$ 93.00

TCI Chemical
(S)-(+)-2-Methylpiperazine >97.0%(T)
5g
$ 192.00

SynQuest Laboratories
(2S)-2-Methylpiperazine 97%
10 g
$ 16.00

SynQuest Laboratories
(2S)-2-Methylpiperazine 97%
100 g
$ 176.00

Sigma-Aldrich
(S)-(+)-2-Methylpiperazine 99%
5g
$ 159.00

Sigma-Aldrich
(S)-(+)-2-Methylpiperazine 99%
1g
$ 45.20

Oakwood
(S)-2-Methylpiperazine 98%
25g
$ 28.00

Total 140 raw suppliers

Chemical Property of (S)-(+)-2-Methylpiperazine

Chemical Property:

Appearance/Colour:white to yellow crystalline powder or chunks
Melting Point:91-93 °C(lit.)
Refractive Index:1.4378 (estimate)
Boiling Point:153.2 °C at 760 mmHg
PKA:9.31±0.40(Predicted)
Flash Point:45.1 °C
PSA：24.06000
Density:0.845 g/cm₃
LogP:0.22530
Storage Temp.:Flammables area
Sensitive.:Air Sensitive & Hygroscopic
Water Solubility.:soluble
XLogP3:-0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:100.100048391
Heavy Atom Count:7
Complexity:54

Purity/Quality:

99% ^*data from raw suppliers

(2S)-2-Methylpiperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): F, Xi, C
Hazard Codes:F,Xi,C
Statements: 11-36/37/38-34
Safety Statements: 16-26-36/37/39-45-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNCCN1
Isomeric SMILES:C[C@H]1CNCCN1
Uses Valuable synthon for quinoline antibacterials.

Technology Process of (S)-(+)-2-Methylpiperazine

There total 3 articles about (S)-(+)-2-Methylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 109-07-9
(RS)-2-methylpiperazine

: 75336-86-6
(2R)-methylpiperazine

: 74879-18-8
(S)-2-methylpiperazine

Guidance literature:: (RS)-2-methylpiperazine; With L-Tartaric acid; In water; acetic acid; at 85 ℃;

With calcium hydroxide; In water; at 80 ℃; for 5h; Reagent/catalyst; Solvent; Temperature;

Reference yield:

: 107-15-3,85404-18-8
ethylenediamine

: 78-98-8
2-oxopropanal

: 75336-86-6
(2R)-methylpiperazine

: 74879-18-8
(S)-2-methylpiperazine

Guidance literature:: With glucose-6-phosphate dehydrogenase; glucose-6-phosphate; Paenibacillus elgii S-selective imine reductase; NADPH; magnesium chloride; In aq. phosphate buffer; at 25 ℃; for 6h; pH=7; enantioselective reaction; Enzymatic reaction;
DOI:10.1021/acscatal.8b00291

Reference yield:

: 107-21-1
ethylene glycol

: 78-90-0,10424-38-1
1,2-diaminopropan

: 75336-86-6
(2R)-methylpiperazine

: 74879-18-8
(S)-2-methylpiperazine

Guidance literature:: With palladium on magnesium oxide; In acetonitrile; at 160 ℃; for 20h; Autoclave; Inert atmosphere;
DOI:10.1002/chem.200901501