7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester

Base Information

Chemical Name:7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester
CAS No.:64595-24-0
Molecular Formula:C₂₈H₄₄O₇
Molecular Weight:492.653
Hs Code.:

Synonyms:7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester

Suppliers and Price of 7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester

Chemical Property:

Melting Point:148 - 150 °C
PSA：99.13000
LogP:4.28860

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester

There total 4 articles about 7α,12α-Bis(acetyloxy)-3α-hydroxy-24-nor-5β-cholan-23-oic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

: 67-56-1
methanol

: 51102-08-0
3α,7α,12α-triacetoxy-24-nor-5β-cholan-23-oic acid

: 64595-24-0
methyl 7α,12α-diacetoxy-3α-hydroxy-24-nor-5β-cholan-23-oate

Guidance literature:: With acetyl chloride; at 25 ℃; for 1h;
DOI:10.1002/prac.19973390135

Reference yield:

: 60696-62-0
24-norcholic acid

: 64595-24-0
methyl 7α,12α-diacetoxy-3α-hydroxy-24-nor-5β-cholan-23-oate

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / pyridine, 4-dimethylaminopyridine / 3.5 h

2: acetyl chloride

With pyridine; dmap; acetyl chloride;
DOI:10.1080/00397919708004196