rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin

Base Information

Chemical Name:rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin
CAS No.:380636-42-0
Molecular Formula:C17H14O4
Molecular Weight:282.296
Hs Code.:
Mol file:380636-42-0.mol

Synonyms:rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin;3,4-Dihydro-2-oxo-4-phenyl-2H-1-benzopyran-6-carboxylic Acid Methyl Ester

Suppliers and Price of rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
rac 6-methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin
5mg
$ 425.00

TRC
rac6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin
25mg
$ 330.00

TRC
rac6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin
5mg
$ 85.00

American Custom Chemicals Corporation
METHYL 2-OXO-4-PHENYL-6-CHROMANECARBOXYLATE 95.00%
100MG
$ 1732.50

American Custom Chemicals Corporation
METHYL 2-OXO-4-PHENYL-6-CHROMANECARBOXYLATE 95.00%
10MG
$ 721.88

Total 5 raw suppliers

Chemical Property of rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin

Chemical Property:

PSA：52.60000
LogP:2.91420
Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

98%Min ^*data from raw suppliers

rac 6-methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin (cas# 380636-42-0) is a compound useful in organic synthesis.

Technology Process of rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin

There total 7 articles about rac 6-Methoxycarbonyl-4-phenyl-3,4-dihydrocoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 91136-58-2
methyl 2-oxo-2H-chromene-6-carboxylate

: 98-80-6
phenylboronic acid

: 380636-42-0
methyl (R)-2-oxo-4-phenylchromane-6-carboxylate

Guidance literature:: With bis(ethylene)rhodium acetylacetonate; (R)-segphos; In 1,4-dioxane; water; at 60 ℃; for 8h;
DOI:10.1021/ol0507367

Reference yield: 65.0%

: 67-56-1
methanol

: 960373-32-4
(R)-4-phenyl-2-chromanone-6-carbonyl chloride

: 380636-42-0
methyl (R)-2-oxo-4-phenylchromane-6-carboxylate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 18h;

Reference yield:

: 140-10-3
(E)-3-phenylacrylic acid

: 380636-42-0
methyl (R)-2-oxo-4-phenylchromane-6-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: sulfuric acid; acetic acid / 18 h / 100 °C

2: butanone / 18 h / 20 °C / Heating / reflux

3: hydrogenchloride; water / ethyl acetate / 1 h / 20 °C

4: pyridine; thionyl chloride / toluene / 2.5 h / 20 - 100 °C

5: triethylamine / tetrahydrofuran / 18 h / 0 - 20 °C

With pyridine; hydrogenchloride; thionyl chloride; sulfuric acid; water; acetic acid; triethylamine; In tetrahydrofuran; ethyl acetate; toluene; butanone;