Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Base Information

Chemical Name:Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate
CAS No.:951625-93-7
Molecular Formula:C9H7ClN2O2
Molecular Weight:210.62
Hs Code.:2933990090
Mol file:951625-93-7.mol

Synonyms:Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate;4-Chloro-7-azaindole-5-carboxylic acid Methyl ester;1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 4-chloro-, Methyl ester;Methyl 4-chloro-7-azaindole-5-carboxylate

Suppliers and Price of Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate
1g
$ 45.00

SynQuest Laboratories
Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 97.0%
250 mg
$ 600.00

SynQuest Laboratories
Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 97.0%
1 g
$ 1720.00

Matrix Scientific
Methyl4-chloro-7-azaindole-5-carboxylate 97.0%
1g
$ 1337.00

Crysdot
Methyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 98%
1g
$ 216.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,methylester 99.77%
1g
$ 202.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,methylester 99.77%
250mg
$ 80.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,methylester 99.77%
100mg
$ 66.00

Chemenu
methyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 95%+
100mg
$ 76.00

Chemenu
methyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 95%+
1g
$ 268.00

Total 25 raw suppliers

Chemical Property of Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Chemical Property:

PSA：54.98000
LogP:2.00290
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

Methyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

There total 4 articles about Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 685513-97-7
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester

: 951625-93-7
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 55052-28-3
4-chloro-7-azaindole

: 951625-93-7
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C

1.2: 20 °C

2.1: sec.-butyllithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -78 °C

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C

With tetrabutyl ammonium fluoride; sec.-butyllithium; sodium hydride; In tetrahydrofuran;

Reference yield:

: 67-56-1
methanol

: 920966-03-6
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

: 951625-93-7
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester

Guidance literature:: 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 18h; Inert atmosphere;

methanol; In dichloromethane; for 2h;