N-(3-Hydroxy-2,6-dimethylphenyl)acetamide

Base Information

Chemical Name:N-(3-Hydroxy-2,6-dimethylphenyl)acetamide
CAS No.:100445-95-2
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID00439553
Nikkaji Number:J654.019H
Wikidata:Q82255528
Mol file:100445-95-2.mol

Synonyms:N-(3-Hydroxy-2,6-dimethylphenyl)acetamide;100445-95-2;3-Acetamido-2,4-dimethylphenol;N-(3-hydroxy-2,6-dimethyl-phenyl)acetamide;SCHEMBL10676572;DTXSID00439553;TVLUGNBVBWVYLD-UHFFFAOYSA-N;CS-T-00160;N-(2,6-Dimethyl-3-hydroxyphenyl)acetamide;FT-0660982;EN300-137963

Suppliers and Price of N-(3-Hydroxy-2,6-dimethylphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Acetamido-2,4-dimethylphenol
100mg
$ 165.00

Medical Isotopes, Inc.
3-Acetamido-2,4-dimethylphenol
1 g
$ 2200.00

AK Scientific
N-(3-Hydroxy-2,6-dimethylphenyl)acetamide
2.5g
$ 1949.00

AK Scientific
N-(3-Hydroxy-2,6-dimethylphenyl)acetamide
500mg
$ 835.00

AK Scientific
N-(3-Hydroxy-2,6-dimethylphenyl)acetamide
250mg
$ 567.00

Total 2 raw suppliers

Chemical Property of N-(3-Hydroxy-2,6-dimethylphenyl)acetamide

Chemical Property:

Boiling Point:334.4±30.0 °C(Predicted)
PKA:10.17±0.23(Predicted)
PSA：49.33000
Density:1.167±0.06 g/cm3(Predicted)
LogP:2.04040
Storage Temp.:-20°C Freezer
Solubility.:Dichloromethane, Methanol
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

3-Acetamido-2,4-dimethylphenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=C(C=C1)O)C)NC(=O)C
Uses 3-Acetamido-2,4-dimethylphenol is used in the preparation of Mepivacaine (M225060) metabolites as well as pyrrolizidine derivatives with antiarrhythmic activity.

Technology Process of N-(3-Hydroxy-2,6-dimethylphenyl)acetamide

There total 10 articles about N-(3-Hydroxy-2,6-dimethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1-acetamido-3-amino-2,6-dimethylbenzene

: 100445-95-2
N-(3-hydroxy-2,6-dimethylphenyl)acetamide

Guidance literature:: 1-acetamido-3-amino-2,6-dimethylbenzene; With sulfuric acid; sodium nitrite; In water; at 0 ℃; for 0.5h;

With urea; In water; at 100 ℃; for 2h;

Reference yield:

: 1,5-dimethyl-5-(3-nitrobenzoyloxy)-6-acetyliminocyclohexa-1,3-diene

: 6337-56-0
N-(4-hydroxy-2,6-dimethylphenyl)acetamide

: 100445-95-2
N-(3-hydroxy-2,6-dimethylphenyl)acetamide

: 3,5-dimethyl-4-acetamidophenyl 3-nitrobenzoate

: 2,4-dimethyl-3-acetamidophenyl 3-nitrobenzoate

: 121-92-6
3-nitrobenzoic acid

Guidance literature:: With sodium perchlorate; In acetonitrile; at 40 ℃; Rate constant; Mechanism; other 1,5-dimethyl-5-aryloxy-6-N-acetyliminocyclohexa-1,3-dienes; var. pH;

Reference yield:

: 167968-06-1
1,5-dimethyl-5-(benzoyloxy)-6-acetyliminocyclohexa-1,3-diene

: 100445-95-2
N-(3-hydroxy-2,6-dimethylphenyl)acetamide

: 65-85-0,8013-63-6
benzoic acid

: 2,4-dimethyl-3-acetamidophenyl benzoate

Guidance literature:: With sodium perchlorate; In acetonitrile; at 40 ℃; Rate constant; other 1,5-dimethyl-5-aroyloxy-6-N-acetyliminocyclohexa-1,3-dienes; var. pH;