6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Base Information

Chemical Name:6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine
CAS No.:746667-09-4
Molecular Formula:C15H12N6
Molecular Weight:276.3
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10440094
Wikidata:Q82256291
Mol file:746667-09-4.mol

Synonyms:6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine;746667-09-4;6-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-[1,2,4]triazolo[1,5-a]pyridine;SCHEMBL5138651;DTXSID10440094

Suppliers and Price of 6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine 95+%
1g
$ 772.00

American Custom Chemicals Corporation
6-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 95.00%
5MG
$ 496.51

Total 6 raw suppliers

Chemical Property of 6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Chemical Property:

PSA：71.76000
LogP:2.48980
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:276.11234441
Heavy Atom Count:21
Complexity:364

Purity/Quality:

95+% ^*data from raw suppliers

6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CC=C1)C2=C(C=NN2)C3=CN4C(=NC=N4)C=C3

Technology Process of 6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

There total 4 articles about 6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 614750-82-2
1-(6-methylpyridin-2-yl)-2-[1,2,4]triazolo-[1,5-a]pyridin-6-yl-ethanone

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 746667-09-4
6-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:: 1-(6-methylpyridin-2-yl)-2-[1,2,4]triazolo-[1,5-a]pyridin-6-yl-ethanone; N,N-dimethyl-formamide dimethyl acetal; at 90 ℃; for 4h;

With hydrazine hydrate; In ethanol; for 3h; Reflux;
DOI:10.1016/j.bmcl.2011.08.064

Reference yield:

: 614750-81-1
[1,2,4]-triazolo[1,5-a]pyridine-6-carbaldehyde

: 746667-09-4
6-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: caesium carbonate / tetrahydrofuran; isopropyl alcohol / 16 h / 20 °C

1.2: 1 h / 20 °C

2.1: 4 h / 90 °C

2.2: 3 h / Reflux

With caesium carbonate; In tetrahydrofuran; isopropyl alcohol;
DOI:10.1016/j.bmcl.2011.08.064

Reference yield:

: 614750-85-5
diphenyl (6-methylpyridin-2-yl)(phenylamino)methylphosphonate

: 746667-09-4
6-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: caesium carbonate / tetrahydrofuran; isopropyl alcohol / 16 h / 20 °C

1.2: 1 h / 20 °C

2.1: 4 h / 90 °C

2.2: 3 h / Reflux

With caesium carbonate; In tetrahydrofuran; isopropyl alcohol;
DOI:10.1016/j.bmcl.2011.08.064