Flurpiridaz (18F)

Base Information

Chemical Name:Flurpiridaz (18F)
CAS No.:863887-89-2
Molecular Formula:C18H22ClFN2O3
Molecular Weight:367.837
Hs Code.:
UNII:TY3V24C029
ChEMBL ID:CHEMBL2107799
DSSTox Substance ID:DTXSID00235517
NCI Thesaurus Code:C171889
Wikidata:Q27290481
Mol file:863887-89-2.mol

Synonyms:BMS 747158-02;BMS-747158-02;BMS747158-02;F-18 BMS-747158-02;flurpiridaz F18

Suppliers and Price of Flurpiridaz (18F)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BMS-747158-02 95.00%
5MG
$ 498.82

Total 4 raw suppliers

Chemical Property of Flurpiridaz (18F)

Chemical Property:

PSA：53.35000
LogP:3.71680
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:367.132833
Heavy Atom Count:25
Complexity:523

Purity/Quality:

99% ^*data from raw suppliers

BMS-747158-02 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)N1C(=O)C(=C(C=N1)OCC2=CC=C(C=C2)COCCF)Cl
Isomeric SMILES:CC(C)(C)N1C(=O)C(=C(C=N1)OCC2=CC=C(C=C2)COCC[18F])Cl
Recent ClinicalTrials:A Study of Flurpiridaz (18F) Injection for PET Imaging for Assessment of MPI Quality Using HPLC and SPE Manufacturing Processes
Recent EU Clinical Trials:A Phase 3, Open-Label, Multicentre Study of Flurpiridaz (F 18) Injection for Positron Emission Tomography (PET) Imaging for Assessment of Myocardial Perfusion in Patients Referred for Invasive Coronary Angiography Because of Suspected Coronary Artery Disease.

Technology Process of Flurpiridaz (18F)

There total 16 articles about Flurpiridaz (18F) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 863888-32-8
toluene 4-sulfonic acid 2-[4-(1-tert-butyl-5-chloro-6-oxo-1,6-dihydro-pyridazin-4-yloxymethyl)-benzyloxy]-ethyl ester

: 863887-89-2
(2-tert-butyl-4-chloro-5-(4-2-(¹⁸F)fluoroethoxymethyl)-benzyloxy)-2H-pyridazin-3-one

Guidance literature:: With tetraethylammonium (F¹⁸)-flouride; tetraethylammonium bicarbonate; In acetonitrile; at 90 ℃; for 0.166667h; Product distribution / selectivity;