(S)-2-phenyl-1-(thiazol-2-yl)ethanamine

Base Information

Chemical Name:(S)-2-phenyl-1-(thiazol-2-yl)ethanamine
CAS No.:1369532-69-3
Molecular Formula:C₁₄H₁₄BrN₃O₂
Molecular Weight:336.188
Hs Code.:
Mol file:1369532-69-3.mol

Synonyms:8-bromo-1-((S)-2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one;8-Bromo-1,3-dihydro-1-[(2S)-2-methoxypropyl]-2H-imidazo[4,5-c]quinolin-2-one;8-bromo-1-[(2S)-2-methoxypropyl]-3H-imidazo[4,5-c]quinolin-2-one

Suppliers and Price of (S)-2-phenyl-1-(thiazol-2-yl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 95+%
250mg
$ 590.00

Crysdot
(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 95+%
1g
$ 1180.00

Crysdot
(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 95+%
100mg
$ 325.00

Alichem
(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one
1g
$ 1780.80

Alichem
(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one
250mg
$ 698.88

Alichem
(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one
100mg
$ 436.80

Total 5 raw suppliers

Chemical Property of (S)-2-phenyl-1-(thiazol-2-yl)ethanamine

Chemical Property:

PKA:11.40±0.20(Predicted)
PSA：59.91000
Density:1.507±0.06 g/cm3(Predicted)
LogP:2.67520

Purity/Quality:

98% ^*data from raw suppliers

(S)-8-Bromo-1-(2-methoxypropyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-phenyl-1-(thiazol-2-yl)ethanamine

There total 5 articles about (S)-2-phenyl-1-(thiazol-2-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1386874-30-1,1369532-19-3
6-bromo-4-[[(2S)-2-methoxypropyl]amino]quinoline-3-carboxylic acid

: 1369532-69-3
8-bromo-1-[(2S)-2-methoxypropyl]-3H-imidazo[4,5-c]quinolin-2-one

Guidance literature:: With diphenyl phosphoryl azide; triethylamine; In N,N-dimethyl-formamide; at 70 ℃; for 1.5h;

Reference yield:

: 122794-99-4
6-bromo-4-hydroxyquinoline-3-carboxylic acid ethyl ester

: 1369532-69-3
8-bromo-1-[(2S)-2-methoxypropyl]-3H-imidazo[4,5-c]quinolin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: trichlorophosphate / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / ethanol / 16 h / 50 °C

3.1: sodium hydroxide; water / tetrahydrofuran / 18 h / 50 °C

3.2: 0.5 h / 0 - 23 °C / pH 6

4.1: triethylamine; diphenyl phosphoryl azide / N,N-dimethyl-formamide / 1.5 h / 70 °C

With diphenyl phosphoryl azide; water; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; trichlorophosphate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 101937-44-4
diethyl 2-((4-bromophenylamino)methylene)malonate

: 1369532-69-3
8-bromo-1-[(2S)-2-methoxypropyl]-3H-imidazo[4,5-c]quinolin-2-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: 2-methyltetrahydrofuran / 240 - 260 °C / 29736.8 - 36201.3 Torr / Inert atmosphere

2.1: trichlorophosphate / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine / ethanol / 16 h / 50 °C

4.1: sodium hydroxide; water / tetrahydrofuran / 18 h / 50 °C

4.2: 0.5 h / 0 - 23 °C / pH 6

5.1: triethylamine; diphenyl phosphoryl azide / N,N-dimethyl-formamide / 1.5 h / 70 °C

With diphenyl phosphoryl azide; water; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; trichlorophosphate; In tetrahydrofuran; 2-methyltetrahydrofuran; ethanol; N,N-dimethyl-formamide;