L-Tyrosine, 3,5-dibroMo-, Methyl ester, hydrochloride (1:1)

Base Information

• Chemical Name: L-Tyrosine, 3,5-dibroMo-, Methyl ester, hydrochloride (1:1)
• CAS No.: 61039-29-0
• Molecular Formula: C10H12Br2ClNO3
• Molecular Weight: 389.46818
• Mol file: 61039-29-0.mol

Synonyms:L-Tyrosine, 3,5-dibroMo-, Methyl ester, hydrochloride (1:1);(S)-Methyl 2-aMino-3-(3,5-dibroMo-4-hydroxyphenyl)propanoate hydrochloride

Chemical Property of L-Tyrosine, 3,5-dibroMo-, Methyl ester, hydrochloride (1:1)

Chemical Property:

• PSA: 72.55000
• LogP: 3.46230

Purity/Quality:

97% ^*data from raw suppliers

(S)-Methyl2-amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoatehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Tyrosine, 3,5-dibroMo-, Methyl ester, hydrochloride (1:1)

There total 3 articles about L-Tyrosine, 3,5-dibroMo-, Methyl ester, hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 3,5-dibromo-DL-tyrosine (537-24-6) → 2-Amino-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid methyl ester; hydrochloride (61039-29-0)

Guidance literature:

With hydrogenchloride; at 60 ℃; for 1.5h;

DOI:10.1021/ac00240a029

Reference yield:

N-formyl-3,5-dibromotyrosine methyl ester (107589-78-6) → 3,5-dibromotyrosine methyl ester hydrochloride (61039-29-0)

Guidance literature:

With hydrogenchloride; In methanol; for 0.416667h; Yield given; Ambient temperature;

DOI:10.1016/S0040-4039(00)84984-9

Reference yield:

N-formyl-L-tyrosine methyl ester (57085-27-5) → 3,5-dibromotyrosine methyl ester hydrochloride (61039-29-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / Br₂, AcONa / 0.58 h / 0 °C

2: 2M HCl / methanol / 0.42 h / Ambient temperature

With hydrogenchloride; bromine; sodium acetate; In methanol;

DOI:10.1016/S0040-4039(00)84984-9

upstream raw materials:

N-formyl-3,5-dibromotyrosine methyl ester

N-formyl-L-tyrosine methyl ester

methanol

3,5-dibromo-DL-tyrosine

Downstream raw materials:

(S)-3-(3,5-Dibromo-4-hydroxy-phenyl)-2-[(S)-3-(3,5-dibromo-4-hydroxy-phenyl)-2-formylamino-propionylamino]-propionic acid methyl ester

N-tert-butoxycarbonyl-L-threonyl-o,o'-dibromo-L-tyrosine methyl ester

C₃₉H₃₄N₂O₄

C₃₉H₃₈N₂O₂