(E)-Methyl 3-(2-nitrophenyl)acrylate

Base Information

• Chemical Name: (E)-Methyl 3-(2-nitrophenyl)acrylate
• CAS No.: 612-43-1
• Molecular Formula: C₁₀H₉NO₄
• Molecular Weight: 207.186
• Hs Code.: 2916399090
• NSC Number: 4156
• Nikkaji Number: J596.514D,J95.588D
• ChEMBL ID: CHEMBL2148187
• Mol file: 612-43-1.mol

Synonyms:(E)-Methyl 3-(2-nitrophenyl)acrylate;612-43-1;39228-29-0;methyl 2-nitrocinnamate;3-(2-NITRO-PHENYL)-ACRYLIC ACID METHYL ESTER;E-Methyl 2-nitrocinnamate;methyl (E)-3-(2-nitrophenyl)prop-2-enoate;2-Nitrobenzeneacrylic acid methyl ester;CHEMBL2148187;methyl3-(2-nitrophenyl)acrylate;METHYL (2E)-3-(2-NITROPHENYL)PROP-2-ENOATE;NSC4156;methyl-2-nitrocinnamate;SCHEMBL1019784;AMY4859;methyl 3-(2-nitrophenyl)acrylate;VKKNUVQQEHKTCG-VOTSOKGWSA-N;NSC-4156;BDBM50391695;MFCD00031068;AKOS002112405;methyl 3-(2-nitrophenyl)prop-2-enoate;2-Nitro-trans-cinnamic acid methyl ester;methyl (2E)-3-(2-nitrophenyl)acrylate;AS-58005;AS-64188;methyl trans-3-(2'-nitrophenyl)propenoate;CS-0158435;CS-0368483;W10677;EN300-7403159;3-(2-NITRO-PHENYL)-ACRYLICACIDMETHYLESTER;SR-01000102258;SR-01000102258-1

Chemical Property of (E)-Methyl 3-(2-nitrophenyl)acrylate

Chemical Property:

• Vapor Pressure: 7.11E-05mmHg at 25°C
• Melting Point: 72 °C
• Boiling Point: 343.3°C at 760 mmHg
• Flash Point: 160.9°C
• PSA: 72.12000
• Density: 1.277g/cm³
• LogP: 2.30420
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 207.05315777
• Heavy Atom Count: 15
• Complexity: 269

Purity/Quality:

97% ^*data from raw suppliers

3-(2-Nitro-phenyl)-acrylicacidmethylester 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)C=CC1=CC=CC=C1[N+](=O)[O-]
• Isomeric SMILES: COC(=O)/C=C/C1=CC=CC=C1[N+](=O)[O-]

Technology Process of (E)-Methyl 3-(2-nitrophenyl)acrylate

There total 20 articles about (E)-Methyl 3-(2-nitrophenyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 2-nitrocinnamic acid (612-41-9) → methyl 2-nitrocinnamate (39228-29-0,105376-46-3,612-43-1)

Guidance literature:

With sulfuric acid; at 75 ℃; for 5h;

Reference yield: 95.0%

o-nitroiodobenzene (609-73-4) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → methyl 2-nitrocinnamate (39228-29-0,105376-46-3,612-43-1)

Guidance literature:

With potassium carbonate; In water; at 90 ℃; for 2h;

DOI:10.1016/j.tet.2016.11.027

Reference yield: 95.0%

methoxycarbonylmethyltriphenylphosphonium iodide (39720-65-5) + 2-nitro-benzaldehyde (552-89-6) → methyl 2-nitrocinnamate (39228-29-0,105376-46-3,612-43-1)

Guidance literature:

With sodium t-butanolate; In tetrahydrofuran; at 25 ℃; for 25h; Temperature; Reagent/catalyst; Schlenk technique; Inert atmosphere;

upstream raw materials:

methyl cinnamate

methanol

2-nitrocinnamic acid

methyl (triphenylphosphoranylidene)acetate

Downstream raw materials:

o-nitrocinnamamide

methyl β-(o-aminophenyl)acrylate

2-nitrocinnamic acid

indole-2-carboxylic acid methyl ester