Ethyl 2-(diethylamino)-2-phenylacetate

Base Information

Chemical Name:Ethyl 2-(diethylamino)-2-phenylacetate
CAS No.:6797-70-2
Molecular Formula:C14H21NO2
Molecular Weight:235.326
Hs Code.:
DSSTox Substance ID:DTXSID90395952
Nikkaji Number:J1.845.690G
Mol file:6797-70-2.mol

Synonyms:ethyl 2-(diethylamino)-2-phenylacetate;6797-70-2;ALPHA-(DIETHYLAMINO)BENZENEACETIC ACID ETHYL ESTER;AC1MWQQI;starbld0001972;SCHEMBL8024263;DTXSID90395952;Phenyl(diethylamino)acetic acid ethyl ester;FT-0666732

Suppliers and Price of Ethyl 2-(diethylamino)-2-phenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-(Diethylamino)benzeneaceticAcidEthylEster
50mg
$ 165.00

Total 2 raw suppliers

Chemical Property of Ethyl 2-(diethylamino)-2-phenylacetate

Chemical Property:

PSA：29.54000
LogP:2.63260
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:235.157228913
Heavy Atom Count:17
Complexity:220

Purity/Quality:

98%min ^*data from raw suppliers

α-(Diethylamino)benzeneaceticAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(C1=CC=CC=C1)C(=O)OCC
Uses α-(DiethylaMino)benzeneacetic Acid Ethyl Ester is an amino ester reagent used in the preparation of α-aminoaldehydes. An amino ester reagent used in the preparation of α-aminoaldehydes.

Technology Process of Ethyl 2-(diethylamino)-2-phenylacetate

There total 17 articles about Ethyl 2-(diethylamino)-2-phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1086217-03-9
(Z)-ethyl 2-(4-toluenesulfonyloxyimino)-2-phenylacetate

: 925-90-6
ethylmagnesium bromide

: 6797-70-2
ethyl 2-(diethylamino)-2-phenylacetate

Guidance literature:: (Z)-ethyl 2-(4-toluenesulfonyloxyimino)-2-phenylacetate; ethylmagnesium bromide; In diethyl ether; toluene; at 30 ℃; for 0.25h; Inert atmosphere;

With water; ammonium chloride; In diethyl ether; toluene; Concentration; Solvent; Temperature; Time;
DOI:10.1246/bcsj.20120195

Reference yield: 85.0%

: (Z)-ethyl 2-toluenesulfonyloxyimino-2-phenylacetate

: 925-90-6
ethylmagnesium bromide

: 6797-70-2
ethyl 2-(diethylamino)-2-phenylacetate

Guidance literature:: (Z)-ethyl 2-toluenesulfonyloxyimino-2-phenylacetate; ethylmagnesium bromide; In diethyl ether; toluene; at 30 ℃; for 0.25h; Inert atmosphere;

With water; ammonium chloride; In diethyl ether; toluene; Concentration; Solvent; Temperature; Time;
DOI:10.1246/bcsj.20120195

Reference yield: 71.0%

: 1418119-50-2
(E)-ethyl 2-(4-toluenesulfonyloxyimino)-2-phenylacetate

: 925-90-6
ethylmagnesium bromide

: 927-77-5
n-propylmagnesium bromide

: 1418119-55-7
ethyl 2-(N-ethyl-N-propylamino)-2-phenylacetate

: 6797-70-2
ethyl 2-(diethylamino)-2-phenylacetate

Guidance literature:: (E)-ethyl 2-(4-toluenesulfonyloxyimino)-2-phenylacetate; ethylmagnesium bromide; With benzoic acid; In diethyl ether; toluene; at -40 ℃; Flow reactor; Inert atmosphere;

n-propylmagnesium bromide; In 1,2-dimethoxyethane; diethyl ether; toluene; at 20 ℃; Reagent/catalyst; Flow reactor; Inert atmosphere;
DOI:10.1055/s-0040-1707265