ethyl 4-amino-2-bromobenzoate

Base Information

• Chemical Name: ethyl 4-amino-2-bromobenzoate
• CAS No.: 109098-70-6
• Molecular Formula: C9H10BrNO2
• Molecular Weight: 244.088
• Mol file: 109098-70-6.mol

Synonyms:4-AMINO-2-BROMOBENZOIC ACID ETHYL ESTER;ethyl 4-amino-2-bromobenzoate

Chemical Property of ethyl 4-amino-2-bromobenzoate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 355.346°C at 760 mmHg
• Flash Point: 168.708°C
• Density: 1.504g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 4-amino-2-bromobenzoate

There total 4 articles about ethyl 4-amino-2-bromobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-bromo-4-nitrobenzoic acid ethyl ester (128566-93-8) → ethyl-2-bromo-4-amino-benzoate (109098-70-6)

Guidance literature:

With water; iron; ammonium chloride; In isopropyl alcohol; at 0 - 100 ℃; for 2h; Inert atmosphere;

Reference yield:

ethanol (64-17-5) + 2-bromo-4-aminobenzoic acid (2486-52-4) → ethyl-2-bromo-4-amino-benzoate (109098-70-6)

Guidance literature:

With sulfuric acid; Heating / reflux;

Reference yield:

ethanol (64-17-5) + 2-bromo-4-nitrotoluene (7745-93-9) → ethyl-2-bromo-4-amino-benzoate (109098-70-6)

Guidance literature:

2-bromo-4-nitrotoluene; With sodium dichromate; sulfuric acid; In acetic acid; at 90 ℃;

With thionyl chloride;

ethanol; With hydrogen; palladium over charcoal; more than 3 stages;

upstream raw materials:

ethanol

2-bromo-4-aminobenzoic acid

2-bromo-4-nitrotoluene

2-bromo-4-nitrobenzoic acid

Downstream raw materials:

C₂₃H₂₄BrF₃N₂O₄