1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1)

Base Information

Chemical Name:1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1)
CAS No.:917918-83-3
Molecular Formula:C8H8Cl2N2O
Molecular Weight:219.07
Hs Code.:2933998090
Mol file:917918-83-3.mol

Synonyms:1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1);7-chloro-4-Methoxy-1H-Pyrrolo[2,3-c]pyridine hydrochloride (1:1);1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1)-8

Suppliers and Price of 1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridineHydrochloride
25mg
$ 265.00

TRC
7-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridineHydrochloride
2.5mg
$ 45.00

SynQuest Laboratories
7-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridine hydrochloride 95%
500 mg
$ 2232.00

Chemenu
7-chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridinehydrochloride 95%+
250mg
$ 930.00

Chemenu
7-chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridinehydrochloride 95%+
100mg
$ 644.00

Chemenu
7-chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridinehydrochloride 95%+
1g
$ 2145.00

AK Scientific
1H-Pyrrolo[2,3-c]pyridine,7-chloro-4-methoxy-,hydrochloride(1:1)
500mg
$ 1488.80

Total 6 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1)

Chemical Property:

PSA：37.91000
LogP:3.02690

Purity/Quality:

NLT 98% ^*data from raw suppliers

7-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1)

There total 2 articles about 1H-Pyrrolo[2,3-c]pyridine, 7-chloro-4-Methoxy-, hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1150310-08-9
C₈H₇ClN₂O*Cl₂HO₂P

: 512-56-1
trimethyl phosphite

: 917918-83-3
C₈H₇ClN₂O*ClH

Guidance literature:: With methanol; In toluene; at 45 - 55 ℃; for 8h; Large scale;
DOI:10.1021/acs.oprd.7b00134

Reference yield:

: 98198-48-2
2-amino-5-bromo-4-methylpyridine

: 917918-83-3
C₈H₇ClN₂O*ClH

Guidance literature:: Multi-step reaction with 7 steps

1.1: sulfuric acid; nitric acid / water / 7 h / 25 - 33 °C / Large scale

2.1: tert.-butylnitrite; sulfuric acid / 9.5 h / 20 - 43 °C / Large scale

3.1: N,N-dimethyl-formamide / 80 - 100 °C / Large scale

4.1: methanol; propanoic acid methyl ester; copper(l) iodide / tetrahydrofuran / 21 h / 30 - 72 °C / Large scale

5.1: 5%-palladium/activated carbon; hydrogen / ethyl acetate / 24 h / 25 - 35 °C / 1275.13 - 1500.15 Torr / Autoclave; Large scale

5.2: 10 - 30 °C / Large scale

6.1: trichlorophosphate / neat (no solvent) / 15 h / 40 - 102 °C / Large scale

7.1: methanol / toluene / 8 h / 45 - 55 °C / Large scale

With methanol; copper(l) iodide; tert.-butylnitrite; propanoic acid methyl ester; sulfuric acid; 5%-palladium/activated carbon; hydrogen; nitric acid; trichlorophosphate; In tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide; toluene; 2.1: |Sandmeyer Reaction / 3.1: |Leimgruber-Batcho Indole Synthesis / 5.1: |Leimgruber-Batcho Indole Synthesis;
DOI:10.1021/acs.oprd.7b00134

Reference yield:

: 917918-83-3
C₈H₇ClN₂O*ClH

: (3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl)methyl di-tert-butyl phosphate

Guidance literature:: Multi-step reaction with 7 steps

1.1: 4-Me-2-pentanol

2.1: isopropylmagnesium chloride / tetrahydrofuran

3.1: N,N,N',N'-tetramethylguanidine / 1-methyl-pyrrolidin-2-one / 2 h / 20 °C / Industry scale; Inert atmosphere

3.2: 18.03 h / 20 °C / Industry scale

4.1: tetrabutoxytitanium / 2-methyltetrahydrofuran / 3 h / Inert atmosphere; Reflux

5.1: chlorine / dichloromethane / -3 - 3 °C / Inert atmosphere; Industry scale

6.1: dichloromethane; water / 20 - 25 °C / Industry scale; Inert atmosphere

7.1: potassium di-tert-butylphosphate; tetraethylammonium bromide / dichloromethane / 1 h / 33 - 42 °C / Inert atmosphere; Industry scale

With tetrabutoxytitanium; tetraethylammonium bromide; isopropylmagnesium chloride; chlorine; potassium di-tert-butylphosphate; N,N,N',N'-tetramethylguanidine; In tetrahydrofuran; 2-methyltetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane; 4-Me-2-pentanol; water;