4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE

Base Information

Chemical Name:4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE
CAS No.:404844-10-6
Molecular Formula:C24H22Cl2N5O
Molecular Weight:466.37
Hs Code.:
Mol file:404844-10-6.mol

Synonyms:4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE

Suppliers and Price of 4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE 95.00%
5MG
$ 502.84

Total 0 raw suppliers

Chemical Property of 4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE

Chemical Property:

PSA：79.80000
LogP:6.52970

Purity/Quality:: 4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE

There total 1 articles about 4-(CHLOROMETHYL)-N-4-METHYL-3-[(4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO]PHENYLBENZAMIDE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 876-08-4
p-(chloromethyl)benzoyl chloride

: 152460-10-1
6-methyl-1-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine

: 404844-10-6
4-(сhloromethyl)-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide hydrochloride

Guidance literature:: In 1,4-dioxane; at 22 - 34 ℃; for 2.75h;
DOI:10.1016/j.bmc.2013.03.038

Reference yield: 52.0%

: 13889-98-0
N-acetylpiperidine

: 404844-10-6
4-(сhloromethyl)-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide hydrochloride

: 1321600-77-4
4-[(4-acetyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 50 ℃; for 18h; Sealed tube;
DOI:10.1016/j.bmc.2013.03.038

Reference yield:

: 7755-92-2
piperazine-1-carbaldehyde

: 404844-10-6
4-(сhloromethyl)-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide hydrochloride

: 1436868-85-7
4-[(4-formyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2pyrimidinyl]-amino]phenyl]benzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 50 ℃; for 18h; Sealed tube;
DOI:10.1016/j.bmc.2013.03.038