N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

Base Information Edit

Chemical Name:N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS No.:152460-10-1
Molecular Formula:C16H15N5
Molecular Weight:277.329
Hs Code.:29335990
European Community (EC) Number:604-859-8
UNII:JR9RZF7KDS
DSSTox Substance ID:DTXSID30433443
Nikkaji Number:J764.280F
Wikidata:Q72439252
ChEMBL ID:CHEMBL278103
Mol file:152460-10-1.mol

Synonyms:152460-10-1;N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine;6-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine;Imatinib amine;2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine;JR9RZF7KDS;4-Methyl-N3-[4-(3-Pyridinyl)-2-Pyrimidinyl]-1,3-Benzenediamine;N-(5-Amino-o-tolyl)-4-(3-pyridyl)-2-pyrimidinamine;CHEMBL278103;N-(5-Amino-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidineamine;4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline;4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine;1,3-Benzenediamine, 4-methyl-N3-(4-(3-pyridinyl)-2-pyrimidinyl)-;1,3-Benzenediamine, 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-;4-Methyl-N*3*-(4-pyridin-3-yl-pyrimidin-2-yl)-benzene-1,3-diamine;4-Methyl-N3-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine;4-Methyl-N3-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine;6-METHYL-N1-[4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL]BENZENE-1,3-DIAMINE;Imatinib Impurity F;Imatinib amine [USP];UNII-JR9RZF7KDS;SCHEMBL2392;DTXSID30433443;QGAIPGVQJVGBIA-UHFFFAOYSA-N;N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine;BCP22918;AC-619;BDBM50287097;MFCD09028125;VCC489937;IMATINIB AMINE [USP IMPURITY];AKOS015888614;AC-2147;CCG-310976;CS-T-03090;CS-W014568;DS-0284;SB60556;112GI007;AM20050827;FT-0647597;FT-0655675;FT-0696298;VU0549314-1;EC 442-110-5;EN300-7372570;Q-100177;F9995-0188;Z1741977607;3-[[4-(3-Pyridinyl)pyrimidine-2-yl]amino]-4-methylaniline;N-(2-methyl-5-amino phenyl)-4-(3-pyridyl) -2-pyrimidinamine;n-(2-methyl-5-aminophenyl)-4-(3-pyridyl)-2-pyrimidine amine;N-(5-Amino-2-methyl phenyl)-4-(3-pyridyl)-2-pyrimidineamine;N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine amine;4-methyl-N~3~-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine;4-methyl-N3-[4-(3-piridinyl)-2-pirimidinyl]-1,3-benzendiamine;4-Methyl-N3-[4-(3-pyridyl)-2-pyrimidinyl]-1,3-phenylenediamine;6-Methyl-N-(4-(pyridine-3-yl)pyrimidin-2-yl)benzene-1,3-diamine;6-Methyl-N1-(4-(pyridine-3-yl)pyrimidin-2-yl)benzene-1,2-diamine;N-(5-amino-2-methyl phenyl)-4-(3-pyridinyl)2-pyrimidine-amine;N-(5-amino-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidine-amine;4-Methyl-N~3~-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine

Suppliers and Price of N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
1g
$ 85.00

TRC
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
2.5g
$ 135.00

TCI Chemical
2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine >98.0%(HPLC)(T)
5g
$ 299.00

TCI Chemical
2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine >98.0%(HPLC)(T)
1g
$ 99.00

SynQuest Laboratories
6-Methyl-N'-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine
100 g
$ 143.00

Medical Isotopes, Inc.
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
0.5 g
$ 2000.00

Matrix Scientific
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 95+%
5g
$ 238.00

Matrix Scientific
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 95+%
1g
$ 80.00

Frontier Specialty Chemicals
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 99%
5g
$ 368.00

Frontier Specialty Chemicals
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 99%
1g
$ 122.00

Total 256 raw suppliers

Chemical Property of N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Edit

Chemical Property:

Appearance/Colour:yellow solid
Vapor Pressure:0mmHg at 25°C
Melting Point:133-135 °C
Refractive Index:1.688
Boiling Point:537.325 °C at 760 mmHg
PKA:4.77±0.10(Predicted)
Flash Point:278.765 °C
PSA：76.72000
Density:1.266 g/cm³
LogP:3.82700
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:277.13274550
Heavy Atom Count:21
Complexity:324

Purity/Quality:

99%, ^*data from raw suppliers

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)N)NC2=NC=CC(=N2)C3=CN=CC=C3
Uses A selective inhibitor of protein kinase C (PKC). N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (Imatinib EP Impurity F) is a selective inhibitor of protein kinase C (PKC). It is a COVID19-related research product.

Technology Process of N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

There total 44 articles about N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%