N-[1-(4-bromophenyl)ethyl]-N,N-dimethylamine hydrochloride

Base Information

• Chemical Name: N-[1-(4-bromophenyl)ethyl]-N,N-dimethylamine hydrochloride
• CAS No.: 140621-51-8
• Molecular Formula: C₁₀H₁₄BrN
• Molecular Weight: 228.132
• Hs Code.: 2921499090
• Mol file: 140621-51-8.mol

Synonyms:N-[1-(4-bromophenyl)ethyl]-N,N-dimethylamine hydrochloride

Chemical Property of N-[1-(4-bromophenyl)ethyl]-N,N-dimethylamine hydrochloride

Chemical Property:

• Boiling Point: 120-122 °C(Press: 14 Torr)
• PKA: 8?+-.0.50(Predicted)
• PSA: 3.24000
• Density: 1.2855 g/cm3
• LogP: 3.87370

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-Bromophenyl)-N,N-dimethylethanamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[1-(4-bromophenyl)ethyl]-N,N-dimethylamine hydrochloride

There total 4 articles about N-[1-(4-bromophenyl)ethyl]-N,N-dimethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-(4-bromophenyl)ethylamine (24358-62-1) → 1-(4'-bromophenyl)-N,N-dimethylethanamine (4187-30-8,140621-51-8)

Guidance literature:

formaldehyd; 1-(4-bromophenyl)ethylamine; With sodium acetate; In methanol; water; at 20 ℃; for 0.0833333h;

With sodium cyanoborohydride; In methanol; water; at 20 ℃; for 2h;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (S)-1-(4-bromophenyl)ethanamine hydrochloride (90006-14-7) → 1-(4'-bromophenyl)-N,N-dimethylethanamine (4187-30-8,140621-51-8)

Guidance literature:

With water; at 130 ℃;

DOI:10.1021/ja01173a014

Reference yield:

para-bromoacetophenone (99-90-1) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 1-(4'-bromophenyl)-N,N-dimethylethanamine (4187-30-8,140621-51-8)

Guidance literature:

With formic acid; magnesium chloride; at 175 ℃;

DOI:10.1021/ja01173a014

upstream raw materials:

formaldehyd

(S)-1-(4-bromophenyl)ethanamine hydrochloride

para-bromoacetophenone

N,N-dimethyl-formamide