Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate

Base Information

Chemical Name:Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate
CAS No.:948995-62-8
Molecular Formula:C23H22N2O8
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID70590822
Nikkaji Number:J2.655.310E
Wikidata:Q82484452
Mol file:948995-62-8.mol

Synonyms:948995-62-8;Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate;(2,5-dioxopyrrolidin-1-yl) 4-[3,5-dimethyl-4-[(4-nitrophenyl)methoxy]phenyl]-4-oxobutanoate;SCHEMBL3628551;DTXSID70590822;CUTCHWUKZOOSRX-UHFFFAOYSA-N;MFCD11973890;succinimidyl4-[3,5-dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate;AKOS015841904;4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyric Acid Succinimidyl Ester;DB-259283;CS-0364975;S0808;D92270;1-[(4-{3,5-Dimethyl-4-[(4-nitrobenzyl)oxy]phenyl}-4-oxobutanoyl)oxy]-2,5-pyrrolidinedione;2,5-dioxopyrrolidin-1-yl 4-(3,5-dimethyl-4-((4-nitrobenzyl)oxy)phenyl)-4-oxobutanoate;1-[(4-{3,5-Dimethyl-4-[(4-nitrophenyl)methoxy]phenyl}-4-oxobutanoyl)oxy]pyrrolidine-2,5-dione;2,5-DIOXOPYRROLIDIN-1-YL 4-{3,5-DIMETHYL-4-[(4-NITROPHENYL)METHOXY]PHENYL}-4-OXOBUTANOATE

Suppliers and Price of Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate >96.0%(HPLC)
100mg
$ 226.00

American Custom Chemicals Corporation
SUCCINIMIDYL 4-(3,5-DIMETHYL-4-(4-NITROBENZYLOXY)PHENYL)-4-OXOBUTYRATE 95.00%
5MG
$ 501.26

AK Scientific
Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate
100mg
$ 353.00

Total 7 raw suppliers

Chemical Property of Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:652.02°C at 760 mmHg
Flash Point:348.129°C
PSA：135.80000
Density:1.391g/cm³
LogP:3.82180
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:454.13761566
Heavy Atom Count:33
Complexity:743

Purity/Quality:

98%,99%, ^*data from raw suppliers

Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate >96.0%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1OCC2=CC=C(C=C2)[N+](=O)[O-])C)C(=O)CCC(=O)ON3C(=O)CCC3=O

Technology Process of Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate

There total 9 articles about Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1012794-99-8
C₁₉H₁₉NO₆

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 948995-62-8
4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1080/00397911.2011.619678

Reference yield:

: 948995-57-1
4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid methyl ester

: 948995-62-8
4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / tetrahydrofuran / 3 h / 20 °C

2: EDAC / CH₂Cl₂ / 3 h / 20 °C

With sodium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo070621b

Reference yield:

: 52246-10-3
4-(4-hydroxy-3,5-dimethylphenyl)-4-oxobutyric acid methyl ester

: 948995-62-8
4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / K₂CO₃ / dimethylformamide / 3 h / 20 °C

2: aq. NaOH / tetrahydrofuran / 3 h / 20 °C

3: EDAC / CH₂Cl₂ / 3 h / 20 °C

With sodium hydroxide; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo070621b