methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate

Base Information

Chemical Name:methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate
CAS No.:1278407-60-5
Molecular Formula:C₁₅H₁₁BrN₂O₂
Molecular Weight:331.169
Hs Code.:
Mol file:1278407-60-5.mol

Synonyms:methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate

Suppliers and Price of methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate

There total 1 articles about methyl 6-bromo-2-phenylH-imidazo[1,2-a]pyridine-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.8%

: 882499-87-8
methyl 2-amino-5-bromo-pyridine-4-carboxylate

: 70-11-1
α-bromoacetophenone

: 1278407-60-5
methyl 6-bromo-2-phenylimidazo[1,2-a]pyridine-7-carboxylate

Guidance literature:: In ethanol; at 100 ℃; for 18h;

Reference yield: 98.0%

: 1278407-60-5
methyl 6-bromo-2-phenylimidazo[1,2-a]pyridine-7-carboxylate

: 1278407-61-6
6-bromo-2-phenylimidazo[1,2-a]pyridine-7-carboxylic acid

Guidance literature:: methyl 6-bromo-2-phenylimidazo[1,2-a]pyridine-7-carboxylate; With water; sodium hydroxide; In ethanol; for 2h; Reflux;

With hydrogenchloride; In ethanol; water; at 0 ℃;

Reference yield:

: 1278407-60-5
methyl 6-bromo-2-phenylimidazo[1,2-a]pyridine-7-carboxylate

: 1278407-36-5
4-(Azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid (6-cyclopropyl-2-phenyl-imidazo[1,2-a]pyridin-7-yl)-amide

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydroxide; water / ethanol / 2 h / Reflux

1.2: 0 °C

2.1: triethylamine; diphenyl phosphoryl azide / Reflux; Inert atmosphere

3.1: potassium phosphate / tricyclohexylphosphine; palladium diacetate / toluene; water / 100 °C / Inert atmosphere

4.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

5.1: N-ethyl-N,N-diisopropylamine; propylphosphonic anhydride / ethyl acetate / 0 - 20 °C

With potassium phosphate; diphenyl phosphoryl azide; propylphosphonic anhydride; water; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; palladium diacetate; tricyclohexylphosphine; In ethanol; dichloromethane; water; ethyl acetate; toluene;