Ethyl hydrogen [(4-methoxyphenyl)methylidene]carbonohydrazonate

Base Information

• Chemical Name: Ethyl hydrogen [(4-methoxyphenyl)methylidene]carbonohydrazonate
• CAS No.: 80214-09-1
• Molecular Formula: C11H14N2O3
• Molecular Weight: 222.2405
• DSSTox Substance ID: DTXSID001001100
• Mol file: 80214-09-1.mol

Synonyms:Maybridge1_005277;DTXSID001001100;Ethyl hydrogen [(4-methoxyphenyl)methylidene]carbonohydrazonate

Chemical Property of Ethyl hydrogen [(4-methoxyphenyl)methylidene]carbonohydrazonate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.11g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 222.10044231
• Heavy Atom Count: 16
• Complexity: 235

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NN=CC1=CC=C(C=C1)OC

Technology Process of Ethyl hydrogen [(4-methoxyphenyl)methylidene]carbonohydrazonate

There total 2 articles about Ethyl hydrogen [(4-methoxyphenyl)methylidene]carbonohydrazonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-methoxy-benzaldehyde (123-11-5) + ethylhydrazine carboxylate (4114-31-2) → ethyl (E)-2-(4-methoxybenzylidene)hydrazine-1-carboxylate (80214-09-1)

Guidance literature:

In ethanol; for 5h; Heating;

DOI:10.1021/je00028a035

Reference yield:

4-methoxy-benzaldehyde (123-11-5) + ethylhydrazine carboxylate (4114-31-2) → C11H14N2O3 (80214-09-1)

Guidance literature:

In ethanol;

DOI:10.1007/s00706-008-0039-9

Reference yield: 94.0%

C11H14N2O3 (80214-09-1) + dimethyl acetylenedicarboxylate (762-42-5) + triphenylphosphine (603-35-0) → dimethyl 2-(2'-(4-methylbenzylidene)-1-(ethoxycarbonyl)hydrazino)-3-(triphenylphosphanylidene)succinate (1210608-84-6)

Guidance literature:

In acetonitrile; at 20 ℃; for 24h;

upstream raw materials:

4-methoxy-benzaldehyde

ethylhydrazine carboxylate

Downstream raw materials:

dimethyl 2-(2'-(4-methylbenzylidene)-1-(ethoxycarbonyl)hydrazino)-3-(triphenylphosphanylidene)succinate

dimethyl 2-cyclohexyliminomethylene-3-[N-ethoxycarbonyl-N'-(4-methoxybenzylidene)hydrazino]succinate