(3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate

Base Information

Chemical Name:(3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate
CAS No.:65429-24-5
Molecular Formula:C₃₃H₆₀O₄Si₂
Molecular Weight:577.008
Hs Code.:
Mol file:65429-24-5.mol

Synonyms:(3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate;(3β,15α,17β)-15,17-Bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]androst-5-en-3-ol Acetate

Suppliers and Price of (3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy)Androst-5-en-3-ol3-O-Acetate
50 mg
$ 1055.00

Biosynth Carbosynth
(3b,15a,17b)-15,17-Bis-O-(tert-butyldimethylsilyloxy) androst-5-en-3-ol 3-O-acetate
50 mg
$ 1310.50

Biosynth Carbosynth
(3b,15a,17b)-15,17-Bis-O-(tert-butyldimethylsilyloxy) androst-5-en-3-ol 3-O-acetate
2 mg
$ 120.00

Biosynth Carbosynth
(3b,15a,17b)-15,17-Bis-O-(tert-butyldimethylsilyloxy) androst-5-en-3-ol 3-O-acetate
25 mg
$ 721.00

Biosynth Carbosynth
(3b,15a,17b)-15,17-Bis-O-(tert-butyldimethylsilyloxy) androst-5-en-3-ol 3-O-acetate
10 mg
$ 396.50

Biosynth Carbosynth
(3b,15a,17b)-15,17-Bis-O-(tert-butyldimethylsilyloxy) androst-5-en-3-ol 3-O-acetate
5 mg
$ 218.10

AK Scientific
[(3R,8R,9S,10R,13S,14S,15S,17S)-15,17-Bis[[tert-butyl(dimethyl)silyl]oxy]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]acetate
2mg
$ 212.00

Total 4 raw suppliers

Chemical Property of (3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate

Chemical Property:

Boiling Point:543.6±50.0 °C(Predicted)
PSA：44.76000
Density:1.00±0.1 g/cm3(Predicted)
LogP:9.27160
Solubility.:Chloroform, Dichloromethane, Ether, Ethyl Acetate

Purity/Quality:

97% ^*data from raw suppliers

(3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy)Androst-5-en-3-ol3-O-Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate in the preparation of Testosterone metabolties.

Technology Process of (3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate

There total 1 articles about (3β,15α,17β)-15,17-Bis-O-(tert-butyldimethylsilyloxy) Androst-5-en-3-ol 3-O-Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 64-19-7,77671-22-8
acetic acid

: 61252-35-5
(1aR,3aR,3bS,5aS,6S,8S,8aS,8bR,10R,10aR)-6-(tert-Butyl-dimethyl-silanyloxy)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-8-ol

: 65429-24-5
3β-Acetoxy-5-androsten-15α,17β-diol-bis-(tert.-butyldimethylsilyl)-ether

Guidance literature:: Multistep reaction; (i) BF₃-Et₂O, THF, Et₂O, (ii) /BRN= 505999/, imidazole, DMF;
DOI:10.1248/cpb.25.2650

Reference yield:

: 65429-24-5
3β-Acetoxy-5-androsten-15α,17β-diol-bis-(tert.-butyldimethylsilyl)-ether

: 2226-70-2
15alpha-Hydroxytestosterone

Guidance literature:: Multi-step reaction with 3 steps

1: aq. KOH / methanol; tetrahydrofuran

2: Al(OiPr)3, MeCOEt / benzene

3: aq. HCl / acetone

With hydrogenchloride; potassium hydroxide; aluminum isopropoxide; butanone; In tetrahydrofuran; methanol; acetone; benzene;
DOI:10.1248/cpb.25.2650