tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate

Base Information

Chemical Name:tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate
CAS No.:1246739-82-1
Molecular Formula:C13H24N2O2
Molecular Weight:240.34186
Hs Code.:
Mol file:1246739-82-1.mol

Synonyms:tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate;tert-butyl 3-pyrrolidinocyclobutyl-carbamate

Suppliers and Price of tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate

Chemical Property:

PSA：45.06000
LogP:2.28020

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate

There total 3 articles about tert-butyl 3-(pyrrolidin-1-yl)cyclobutylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 123-75-1
pyrrolidine

: 878156-25-3
3-((tert-butoxycarbonyl)amino)cyclobutyl 4-methylbenzenesulfonate

: 1246739-82-1
tert-butyl N-[3-(pyrrolidin-1-yl)cyclobutyl]carbamate

Guidance literature:: With dmap; at 70 ℃; Inert atmosphere;

Reference yield:

: 110-52-1
1,4-dibromo-butane

: 1090904-48-5
cis/trans-tert-butyl (3-aminocyclobutyl)carbamate

: 1246739-82-1
tert-butyl N-[3-(pyrrolidin-1-yl)cyclobutyl]carbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 23 - 70 ℃; for 18h;

Reference yield:

: 154748-63-7
tert-butyl ((1s,3s)-3-hydroxycyclobutyl)carbamate

: 1246739-82-1
tert-butyl N-[3-(pyrrolidin-1-yl)cyclobutyl]carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

2: dmap / 70 °C / Inert atmosphere

With dmap; triethylamine; In dichloromethane;