2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol

Base Information

Chemical Name:2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol
CAS No.:1027345-21-6
Molecular Formula:C15H19ClO
Molecular Weight:250.768
Hs Code.:
Mol file:1027345-21-6.mol

Synonyms:2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol;1-Cyclohexene-1-Methanol, 2-(4-chlorophenyl)-5,5-diMethyl-;[2-(4-Chlorophenyl)-5,5-dimethylcyclohex-1-enyl]methanol;(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

Suppliers and Price of 2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol
250 mg
$ 690.00

TRC
2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol
25mg
$ 120.00

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-5,5-DIMETHYL-1-CYCLOHEXENE-1-METHANOL 95.00%
10MG
$ 693.00

Total 3 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol

Chemical Property:

PSA：20.23000
LogP:4.29600
Solubility.:Chloroform, Dichloromethane, Ether, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate in the production of cell death regulators and apoptosis promoters.

Technology Process of 2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol

There total 7 articles about 2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexene-1-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1027345-20-5
methyl 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enecarboxylate

: 1027345-21-6
(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

Guidance literature:: methyl 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enecarboxylate; With lithium aluminium tetrahydride; In diethyl ether; at -10 - 0 ℃; for 2h;

With sodium hydroxide; water; In diethyl ether; at 0 ℃;

Reference yield:

: 1202186-71-7
4-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1-biphenyl]-2-carbaldehyde

: 1027345-21-6
(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; water; at 20 ℃; for 1h;

Reference yield:

: 4255-62-3
4,4-dimethylcyclohexane-1-one

: 1027345-21-6
(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus tribromide / N,N-dimethyl-formamide / 0 - 60 °C

2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; 1,4-dioxane / 3 h / 90 °C / Inert atmosphere

3: sodium tetrahydroborate / tetrahydrofuran; water / 1 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; potassium acetate; phosphorus tribromide; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;