(2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester

Base Information

Chemical Name:(2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester
CAS No.:56145-21-2
Molecular Formula:C₈H₁₄O₆
Molecular Weight:206.196
Hs Code.:
Mol file:56145-21-2.mol

Synonyms:(2R,3R)-2,3-Dimethoxybutanedioic acid dimethyl ester;(2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester

Suppliers and Price of (2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of (2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester

There total 15 articles about (2R,3R)-2,3-Dimethoxysuccinic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 608-68-4
dimethyl L-tartrate

: 74-88-4
methyl iodide

: 62138-50-5,62182-40-5,72719-00-7,56145-21-2
(R,R)-2,3-dimethoxy-succinic acid dimethyl ester

Guidance literature:: With silver(l) oxide; In diethyl ether;
DOI:10.1080/10242430210704

Reference yield: 99.0%

: 13171-64-7
Dimethyl D-tartrate

: 74-88-4
methyl iodide

: 56145-21-2,62138-50-5,62182-40-5,72719-00-7
dimethyl (O,O'-dimethyl)-L-tartrate

Guidance literature:: With silver(l) oxide;
DOI:10.1002/chem.201102902

Reference yield:

: 159299-69-1
(E)-3-((3aS,3bR,7aS,8aS)-2,2,5,5-Tetramethyl-tetrahydro-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxin-8a-yl)-acrylic acid methyl ester

: 62138-50-5,62182-40-5,72719-00-7,56145-21-2
(R,R)-2,3-dimethoxy-succinic acid dimethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 52 percent / KClO₃, 1percent OsO₄ / acetone; H₂O / 30 h / Ambient temperature

2: 86 percent / 1.) NaH, imidazole / 1.) mineral oil, DMSO, THF, 60 deg C, 30 min; 2.) mineral oil, DMSO, THF, 30 min

3: 91 percent / 70percent TFA / H₂O / Ambient temperature

4: NaIO₃, OsO₄ / H₂O

5: methanol / 0.5 h / Ambient temperature

With 1H-imidazole; osmium(VIII) oxide; potassium chlorate; sodium iodate; sodium hydride; trifluoroacetic acid; In methanol; water; acetone;
DOI:10.1016/S0008-6215(98)00076-7