Technology Process of 5-broMo-3-(difluoroMethoxy)-2-Methoxypyridine
There total 5 articles about 5-broMo-3-(difluoroMethoxy)-2-Methoxypyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
silver carbonate;
In
chloroform;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide; water / 4 h / 100 °C
2.1: sodium / 6 h / 100 °C
3.1: boron tribromide / dichloromethane; n-heptane / 20 - 25 °C / Inert atmosphere; Reflux
3.2: pH 7 - 8
4.1: sodium acetate; bromine / acetic acid / 0.67 h / 10 - 15 °C
5.1: silver carbonate / chloroform / 20 - 25 °C
With
bromine; sodium acetate; sodium; boron tribromide; potassium carbonate; silver carbonate;
In
n-heptane; dichloromethane; chloroform; water; acetic acid; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium / 6 h / 100 °C
2.1: boron tribromide / dichloromethane; n-heptane / 20 - 25 °C / Inert atmosphere; Reflux
2.2: pH 7 - 8
3.1: sodium acetate; bromine / acetic acid / 0.67 h / 10 - 15 °C
4.1: silver carbonate / chloroform / 20 - 25 °C
With
bromine; sodium acetate; sodium; boron tribromide; silver carbonate;
In
n-heptane; dichloromethane; chloroform; acetic acid;
