4-Methoxynaphthalen-1-ylboronic acid pinacol ester

Base Information

• Chemical Name: 4-Methoxynaphthalen-1-ylboronic acid pinacol ester
• CAS No.: 269410-16-4
• Molecular Formula: C₁₇H₂₁BO₃
• Molecular Weight: 284.163
• Hs Code.: 2931900090
• Mol file: 269410-16-4.mol

Synonyms:4-Methoxynaphthalen-1-ylboronic acid pinacol ester;2-(4-methoxy-1-naphthalenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-(4-Methoxynaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 4-Methoxynaphthalen-1-ylboronic acid pinacol ester

Chemical Property:

• Boiling Point: 412.2±28.0 °C(Predicted)
• PSA: 27.69000
• Density: 1.08±0.1 g/cm3(Predicted)
• LogP: 3.14760

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Methoxynaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Methoxynaphthalen-1-ylboronic acid pinacol ester

There total 7 articles about 4-Methoxynaphthalen-1-ylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1-bromo-4-methoxynaphthalene (5467-58-3) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-(4-methoxy-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (269410-16-4)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; triethylamine; In 1,4-dioxane; at 100 ℃; for 23h;

Reference yield: 66.0%

4-methoxynaphthalen-1-yl diethylcarbamate (1201594-02-6) + bis(pinacol)diborane (73183-34-3) → 2-(4-methoxy-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (269410-16-4)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; iron(II) acetate; sodium t-butanolate; In di-isopropyl ether; at 120 ℃; for 15h; Schlenk technique; Glovebox; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01937

Reference yield: 56.0%

1-bromo-4-methoxynaphthalene (5467-58-3) + bis(pinacol)diborane (73183-34-3) → 2-(4-methoxy-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (269410-16-4)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In 1,4-dioxane; at 80 ℃; for 12h; Ionic liquid;

DOI:10.1039/c6cc01534d

upstream raw materials:

1-bromo-4-methoxynaphthalene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

1-Methoxynaphthalene