2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine

Base Information

Chemical Name:2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine
CAS No.:1263296-82-7
Molecular Formula:C19H22N2
Molecular Weight:278.397
Hs Code.:2933990090
Mol file:1263296-82-7.mol

Synonyms:2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine;2-(diphenylmethyl)-2-azaspiro[3.3]heptan-5-amine

Suppliers and Price of 2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Synthonix
5-Amino-2-diphenylmethyl-2-azaspiro[3.3]heptane 95+%
1g
$ 1160.00

Synthonix
5-Amino-2-diphenylmethyl-2-azaspiro[3.3]heptane 95+%
250mg
$ 390.00

Matrix Scientific
5-Amino-2-diphenylmethyl-2-azaspiro[3.3]heptane 95+%
1g
$ 2112.00

Crysdot
5-Amino-2-diphenylmethyl-2-azaspiro[3.3]heptane 95+%
1g
$ 579.00

Chemenu
5-Amino-2-diphenylmethyl-2-azaspiro[3.3]heptane 95%
1g
$ 547.00

Alichem
2-Benzhydryl-2-azaspiro[3.3]heptan-5-amine
1g
$ 1100.00

Alichem
2-Benzhydryl-2-azaspiro[3.3]heptan-5-amine
250mg
$ 470.80

Total 8 raw suppliers

Chemical Property of 2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine

Chemical Property:

Boiling Point:393.0±42.0 °C(Predicted)
PKA:10.06±0.20(Predicted)
PSA：29.26000
Density:1.16±0.1 g/cm3(Predicted)
LogP:3.83730

Purity/Quality:

99%, ^*data from raw suppliers

5-Amino-2-diphenylmethyl-2-azaspiro[3.3]heptane 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine

There total 4 articles about 2-benzhydryl-2-azaspiro[3.3]heptan-5-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1263296-81-6
2-benzhydryl-2-azaspiro[3.3]heptan-5-ol

: 1263296-82-7
(R,S)-2-benzhydryl-2-azaspiro[3.3]heptan-5-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/ol103050c

Reference yield:

: 1263296-79-2
6-benzhydryl-6-aza-8-oxa-dispiro[2.0.3.1]octane

: 1263296-82-7
(R,S)-2-benzhydryl-2-azaspiro[3.3]heptan-5-amine

Guidance literature:: Multi-step reaction with 3 steps

1: lithium iodide / tetrahydrofuran; toluene / 15 h / 20 - 50 °C / Inert atmosphere

2: sodium tetrahydroborate / tetrahydrofuran; methanol / 16 h / 20 °C / Inert atmosphere

3: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; lithium aluminium tetrahydride; lithium iodide; In tetrahydrofuran; methanol; toluene;
DOI:10.1021/ol103050c

Reference yield:

: 1263296-80-5
6-(diphenylmethyl)-6-azaspiro[3.3]heptan-1-one

: 1263296-82-7
(R,S)-2-benzhydryl-2-azaspiro[3.3]heptan-5-amine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / tetrahydrofuran; methanol / 16 h / 20 °C / Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; lithium aluminium tetrahydride; In tetrahydrofuran; methanol;
DOI:10.1021/ol103050c