Cyclopentanepropanoic acid, α-amino-, methyl ester, hydrochloride (1:1), (αS)-

Base Information

• Chemical Name: Cyclopentanepropanoic acid, α-amino-, methyl ester, hydrochloride (1:1), (αS)-
• CAS No.: 1191996-99-2
• Molecular Formula: C9H18ClNO2
• Molecular Weight: 207.7
• Hs Code.: 2922499990
• Mol file: 1191996-99-2.mol

Synonyms:Cyclopentanepropanoic acid, α-amino-, methyl ester, hydrochloride (1:1), (αS)-;(S)-Methyl 2-amino-3-cyclopentylpropanoate hydrochloride;(S)-METHYL 2-AMINO-3-CYCLOPENTYLPROPANOATE HCl

Chemical Property of Cyclopentanepropanoic acid, α-amino-, methyl ester, hydrochloride (1:1), (αS)-

Chemical Property:

• PSA: 52.32000
• LogP: 2.56930
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(S)-Methyl2-amino-3-cyclopentylpropanoateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopentanepropanoic acid, α-amino-, methyl ester, hydrochloride (1:1), (αS)-

There total 1 articles about Cyclopentanepropanoic acid, α-amino-, methyl ester, hydrochloride (1:1), (αS)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-cyclopentyl-L-alanine (5455-46-9) + methanol (67-56-1) → (S)-2-amino-3-cyclopentyl-propionic acid methyl ester hydrochloride (1191996-99-2,2514709-11-4)

Guidance literature:

With hydrogenchloride; at 50 ℃; for 18h;

Reference yield: 60.0%

(S)-2-amino-3-cyclopentyl-propionic acid methyl ester hydrochloride (1191996-99-2,2514709-11-4) + 4-bromo-3-(2-chloro-3-methoxy-phenoxy)-but-2-enoic acid ethyl ester (1191997-39-3) → (S)-2-[4-(2-chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-3-cyclopentyl-propionic acid methyl ester (1191997-46-2)

Guidance literature:

(S)-2-amino-3-cyclopentyl-propionic acid methyl ester hydrochloride; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 25 - 80 ℃;

4-bromo-3-(2-chloro-3-methoxy-phenoxy)-but-2-enoic acid ethyl ester; In acetonitrile; at 80 - 100 ℃;

Reference yield: 30.0%

(S)-2-amino-3-cyclopentyl-propionic acid methyl ester hydrochloride (1191996-99-2,2514709-11-4) + 4-bromo-3-(2-methoxy-phenoxy)-but-2-enoic acid ethyl ester (1838-33-1) → (S)-3-cyclopentyl-2-[4-(2-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-propionic acid methyl ester (1191997-10-0)

Guidance literature:

(S)-2-amino-3-cyclopentyl-propionic acid methyl ester hydrochloride; With triethylamine; In acetonitrile; at 25 - 80 ℃;

4-bromo-3-(2-methoxy-phenoxy)-but-2-enoic acid ethyl ester; In acetonitrile; at 80 - 100 ℃;

upstream raw materials:

3-cyclopentyl-L-alanine

methanol

Downstream raw materials:

(S)-3-cyclopentyl-2-[4-(2-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-propionic acid methyl ester

(S)-3-cyclopentyl-2-[4-(2,6-difluoro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-propionic acid methyl ester

(S)-2-[4-(2-chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-3-cyclopentyl-propionic acid methyl ester