(S)-2-cyanoMorpholine

Base Information

• Chemical Name: (S)-2-cyanoMorpholine
• CAS No.: 1359658-57-3
• Molecular Formula: C5H8N2O
• Molecular Weight: 112.12982
• Mol file: 1359658-57-3.mol

Synonyms:(S)-2-cyanoMorpholine;(2S)-2-Morpholinecarbonitrile;(S)-2-cyanomorpholine HCl

Chemical Property of (S)-2-cyanoMorpholine

Chemical Property:

• Boiling Point: 256.0±35.0 °C(Predicted)
• PKA: 6.83±0.40(Predicted)
• Density: 1.10±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

(S)-Morpholine-2-carbonitrilehydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-cyanoMorpholine

There total 1 articles about (S)-2-cyanoMorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanolamine (141-43-5) + 2-Chloroacrylonitrile (920-37-6) → morpholine-2-carbonitrile (135782-24-0,1359658-57-3,1262484-62-7)

Guidance literature:

With potassium tert-butylate; Yield given. Multistep reaction;

DOI:10.1016/S0040-4039(00)79702-4

Reference yield: 80.0%

ethanol (64-17-5) + morpholine-2-carbonitrile (135782-24-0,1359658-57-3,1262484-62-7) → 2-morpholinecarboxylic acid ethyl ester (135782-25-1)

Guidance literature:

With sulfuric acid;

DOI:10.1016/S0040-4039(00)79702-4

upstream raw materials:

ethanolamine

2-Chloroacrylonitrile

Downstream raw materials:

2-morpholinecarboxylic acid ethyl ester