N-[2-Methoxy-4-(methylsulfonylamino)phenyl]acetamide

Base Information

Chemical Name:N-[2-Methoxy-4-(methylsulfonylamino)phenyl]acetamide
CAS No.:83209-82-9
Molecular Formula:C10H14N2O4S
Molecular Weight:258.29
Hs Code.:2935009090
DSSTox Substance ID:DTXSID80357367
Wikidata:Q82137259
Mol file:83209-82-9.mol

Synonyms:N-[2-METHOXY-4-(METHYLSULFONYLAMINO)PHENYL]ACETAMIDE;83209-82-9;N-[4-(methanesulfonamido)-2-methoxyphenyl]acetamide;SCHEMBL11072033;DTXSID80357367;AQ-776/42801538;N-(2-Methoxy-4-(methylsulfonamido)phenyl)acetamide;N-{2-methoxy-4-[(methylsulfonyl)amino]phenyl}acetamide

Suppliers and Price of N-[2-Methoxy-4-(methylsulfonylamino)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-[2-METHOXY-4-(METHYLSULFONYLAMINO)PHENYL]ACETAMIDE 95.00%
5MG
$ 499.51

Total 1 raw suppliers

Chemical Property of N-[2-Methoxy-4-(methylsulfonylamino)phenyl]acetamide

Chemical Property:

PSA：92.88000
LogP:2.25190
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:258.06742811
Heavy Atom Count:17
Complexity:363

Purity/Quality:

97% ^*data from raw suppliers

N-[2-METHOXY-4-(METHYLSULFONYLAMINO)PHENYL]ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=C(C=C(C=C1)NS(=O)(=O)C)OC

Technology Process of N-[2-Methoxy-4-(methylsulfonylamino)phenyl]acetamide

There total 4 articles about N-[2-Methoxy-4-(methylsulfonylamino)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 124-63-0
methanesulfonyl chloride

: 5329-15-7
N-(4-amino-2-methoxyphenyl)acetamide

: 83209-82-9
N-<2-methoxy-4-<(methylsulfonyl)amino>phenyl>acetamide

Guidance literature:: With pyridine; In chloroform; at 0 - 25 ℃; for 2h;
DOI:10.1021/jo00256a036

Reference yield:

: 93-27-6
5-nitro-2-acetylaminoanisole

: 83209-82-9
N-<2-methoxy-4-<(methylsulfonyl)amino>phenyl>acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 5percent palladium on charcoal, hydrogen / ethyl acetate / 3 h

2: 57 percent / pyridine / CHCl₃ / 2 h / 0 - 25 °C

With pyridine; palladium on activated charcoal; hydrogen; In chloroform; ethyl acetate;
DOI:10.1021/jo00256a036

Reference yield:

: 97-52-9
2-methoxy-4-nitrophenylamine

: 83209-82-9
N-<2-methoxy-4-<(methylsulfonyl)amino>phenyl>acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / acetic acid / 1 h / 80 °C

2: H₂ / Raney nickel / methanol / 22.5 h / 2585.7 Torr

3: pyridine / CH₂Cl₂ / 25 °C

With pyridine; hydrogen; nickel; In methanol; dichloromethane; acetic acid;
DOI:10.1002/jhet.5570260542