2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

Base Information

Chemical Name:2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine
CAS No.:1012880-11-3
Molecular Formula:C13H19BFNO2
Molecular Weight:251.109
Hs Code.:
Mol file:1012880-11-3.mol

Synonyms:2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine;2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine;2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Suppliers and Price of 2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine 95%
5g
$ 1980.00

Chemcia Scientific
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine ＞97%
0.5 G
$ 295.00

Ambeed
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 95%
1g
$ 470.00

Ambeed
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 95%
100mg
$ 121.00

Ambeed
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 95%
250mg
$ 188.00

Aaron Chemicals
2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine 95%
250mg
$ 211.00

Aaron Chemicals
2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine 95%
100mg
$ 142.00

A1 Biochem Labs
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine 95%
5 g
$ 1200.00

Total 4 raw suppliers

Chemical Property of 2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

Chemical Property:

Boiling Point:353.3±42.0 °C(Predicted)
PKA:3.63±0.10(Predicted)
PSA：44.48000
Density:1.09±0.1 g/cm3(Predicted)
LogP:2.59670

Purity/Quality:

99%, ^*data from raw suppliers

2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

There total 3 articles about 2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 945244-29-1
5-bromo-2-fluoro-4-methylaniline

: 73183-34-3
bis(pinacol)diborane

: 1012880-11-3
2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 100 ℃; for 16h; Inert atmosphere;

Reference yield:

: 170098-98-3
1-bromo-4-fluoro-2-methyl-5-nitro-benzene

: 1012880-11-3
2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: iron; hydrogenchloride / ethyl acetate; water / 20 - 30 °C / Inert atmosphere

2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / Isopropyl acetate / 50 °C / Inert atmosphere; Reflux

With hydrogenchloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; iron; In Isopropyl acetate; water; ethyl acetate;

Reference yield:

: 452-63-1
2-Bromo-5-fluorotoluene

: 1012880-11-3
2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid; potassium nitrate / -10 - 20 °C / Cooling with ice; Inert atmosphere

2: iron; hydrogenchloride / ethyl acetate; water / 20 - 30 °C / Inert atmosphere

3: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / Isopropyl acetate / 50 °C / Inert atmosphere; Reflux

With hydrogenchloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sulfuric acid; potassium acetate; iron; potassium nitrate; In Isopropyl acetate; water; ethyl acetate;