(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid

Base Information

Chemical Name:(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid
CAS No.:38580-22-2
Molecular Formula:C₇H₈N₂O₄
Molecular Weight:184.152
Hs Code.:2933599090
European Community (EC) Number:874-968-5
DSSTox Substance ID:DTXSID90353491
Wikidata:Q82131113
Mol file:38580-22-2.mol

Synonyms:38580-22-2;(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid;2-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid;2-(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)acetic acid;ASINEX-REAG BAS 03375399;6-methyluracil-5-acetic acid;5-pyrimidineacetic acid, 1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-;MFCD03006091;ChemDiv2_000798;SCHEMBL1227729;DTXSID90353491;GFWWREGOTNQVGC-UHFFFAOYSA-N;HMS1371E06;BBL029834;STK652394;STL514099;AKOS000111435;AKOS023844781;SB56783;VS-09458;BB 0238542;EN300-234924;SR-01000477736;(2,4-dihydroxy-6-methylpyrimidin-5-yl)acetic acid;SR-01000477736-1;F0918-1473;Z274567474;(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)acetic acid;(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimi din-5-yl)-acetic acid;2-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)aceticacid;(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid, AldrichCPR

Suppliers and Price of (6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid 95%
1g
$ 350.00

Matrix Scientific
(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid 95%
5g
$ 1154.00

Matrix Scientific
(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid 95%
2.500g
$ 762.00

ChemBridge Corporation
(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)aceticacid 95%
25 g
$ 356.00

American Custom Chemicals Corporation
(6-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)ACETIC ACID 95.00%
5MG
$ 498.67

AK Scientific
(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)aceticacid
2.5g
$ 263.00

AK Scientific
(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)aceticacid
500mg
$ 185.00

AK Scientific
(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)aceticacid
100mg
$ 166.00

Total 5 raw suppliers

Chemical Property of (6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid

Chemical Property:

PSA：103.02000
Density:1.384g/cm³
LogP:-1.00130
XLogP3:-1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:184.04840674
Heavy Atom Count:13
Complexity:319

Purity/Quality:

99% ^*data from raw suppliers

(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)NC(=O)N1)CC(=O)O
Uses (6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid is used as a reactant in the preparation of pyrimidine derivatives as viral replication inhibitors, useful in treatment of HIV infection.

Technology Process of (6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid

There total 4 articles about (6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 62214-19-1
(6-methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid

: 38580-22-2
5-Carboxymethyl-6-methyluracil

Guidance literature:: With water; chloroacetic acid; for 24h; Reflux;

Reference yield: 31.0%

: 626-48-2
6-Methyluracil

: 64-19-7,77671-22-8
acetic acid

: 38580-22-2
5-Carboxymethyl-6-methyluracil

Guidance literature:: With dibenzoyl peroxide; at 80 ℃; for 7h;

Reference yield:

: 10420-33-4
dimethyl 2-acetylsuccinate

: 38580-22-2
5-Carboxymethyl-6-methyluracil

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium methylate / methanol / 18 h / Reflux

1.2: 0 °C

2.1: water; chloroacetic acid / 24 h / Reflux

With water; sodium methylate; chloroacetic acid; In methanol;