1,2:3,4:5,6-TRI-O-ISOPROPYLIDENE-D-MANNITOL

Base Information

• Chemical Name: 1,2:3,4:5,6-TRI-O-ISOPROPYLIDENE-D-MANNITOL
• CAS No.: 3969-59-3
• Molecular Formula: C15H26 O6
• Molecular Weight: 302.368
• Mol file: 3969-59-3.mol

Synonyms:D-Mannitol,1,2:3,4:5,6-tris-O-(1-methylethylidene)- (9CI); Mannitol,1,2:3,4:5,6-tri-O-isopropylidene-, D- (6CI,7CI,8CI);1,2:3,4:5,6-Tri-O-isopropylidene-D-mannitol; NSC 20733

Chemical Property of 1,2:3,4:5,6-TRI-O-ISOPROPYLIDENE-D-MANNITOL

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 342.8 °C at 760 mmHg
• Flash Point: 132.2 °C
• PSA: 55.38000
• Density: 1.099 g/cm³
• LogP: 1.80950
• Storage Temp.: 2-8°C

Purity/Quality:

98%, ^*data from raw suppliers

1,2:3,4:5,6-Tri-O-isopropylidene-D-mannitol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 1,2:3,4:5,6-TRI-O-ISOPROPYLIDENE-D-MANNITOL

There total 9 articles about 1,2:3,4:5,6-TRI-O-ISOPROPYLIDENE-D-MANNITOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

mannitol (69-65-8) + 2,2-dimethoxy-propane (77-76-9) → 1,2:5,6-di-O-isopropylidene-D-mannitol (1707-77-3) + mannitol triacetonide (3969-59-3)

Guidance literature:

With Montmorillonite K₁₀ clay; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2004.05.079

Reference yield: 29.0%

mannitol (69-65-8) + 2,2-dimethoxy-propane (77-76-9) → 1,2-mono-O-isopropylidene-D-mannitol (4306-35-8) + 1,2:3,4-di-O-isopropylidene-D-mannitol (38145-93-6) + 1,2:5,6-di-O-isopropylidene-D-mannitol (1707-77-3) + mannitol triacetonide (3969-59-3)

Guidance literature:

In 1,2-dimethoxyethane; Heating;

DOI:10.1016/S0008-6215(00)85208-8

Reference yield: 4.2%

mannitol (69-65-8) + acetone (67-64-1) → 1,2:3,6:4,5-tri-O-isopropylidene-D-mannitol (91667-55-9) + 1,2:5,6-di-O-isopropylidene-D-mannitol (1707-77-3) + mannitol triacetonide (3969-59-3)

Guidance literature:

With zinc(II) chloride; at 20 ℃; for 22h;

DOI:10.1016/0008-6215(84)85087-9

upstream raw materials:

mannitol

2-Methoxypropene

2,2-dimethoxy-propane

acetone

Downstream raw materials:

3,4-di-O-isopropylidene-D-mannitol

D-glucitol

3,4-O-isopropylidene-D-glucitol

1,2:3,4-di-O-isopropylidene-D-glucitol