Deferasirox Ethyl Ester

Base Information

Chemical Name:Deferasirox Ethyl Ester
CAS No.:201530-79-2
Molecular Formula:C23H19N3O4
Molecular Weight:401.41
Hs Code.:

Synonyms:Deferasirox Ethyl Ester

Suppliers and Price of Deferasirox Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DeferasiroxEthylEster
250mg
$ 215.00

Medical Isotopes, Inc.
DeferasiroxEthylEster
100 mg
$ 2200.00

Total 9 raw suppliers

Chemical Property of Deferasirox Ethyl Ester

Chemical Property:

Boiling Point:638.4±65.0 °C(Predicted)
PKA:8.02±0.35(Predicted)
PSA：97.47000
Density:1.31±0.1 g/cm3(Predicted)
LogP:4.18920
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

99%, ^*data from raw suppliers

DeferasiroxEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Deferasirox Ethyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.

Technology Process of Deferasirox Ethyl Ester

There total 6 articles about Deferasirox Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 64-17-5
ethanol

: 201530-41-8
deferasirox

: 201530-79-2
4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid ethyl ester

Guidance literature:: With sulfuric acid; for 23h; Heating;

Reference yield: 76.03%

: 1218-69-5
2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one

: 14685-90-6
4-ethoxycarbonylphenylhydrazine

: 201530-79-2
4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid ethyl ester

Guidance literature:: In methanol; for 3h; Inert atmosphere;
DOI:10.1080/00397911.2011.580068

Reference yield:

: 65-45-2
salicylamide

: 201530-79-2
4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride; pyridine; thionyl chloride / ethanol; o-xylene / 2 h / 120 - 125 °C

2: methanol / 3 h / Inert atmosphere

With pyridine; aluminum (III) chloride; thionyl chloride; In methanol; ethanol; o-xylene;
DOI:10.1080/00397911.2011.580068