14685-90-6

Basic information

• Product Name: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER
• Synonyms: ethyl 4-hydrazinobenzoate(SALTDATA: HCl);4-(1-ethylhydrazin-1-yl)benzoate;Benzoic acid, 4-hydrazino-, ethyl ester;Benzoic acid,4-hydrazinyl-, ethyl ester
• CAS NO: 14685-90-6
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.2
• Mol File: 14685-90-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 118 °C
• Boiling Point: 329.9°C at 760 mmHg
• Flash Point: 153.3°C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 0.000172mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.39±0.20(Predicted)
• CAS DataBase Reference: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER(14685-90-6)
• EPA Substance Registry System: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER(14685-90-6)

Safety Data

• Hazardous Substances Data: 14685-90-6(Hazardous Substances Data)

Usage

Uses

Ethyl 4-Hydrazinylbenzoate can be used to treat alzheimer’s disease.

InChI:InChI=1/C9H12N2O2/c1-2-13-9(12)7-3-5-8(11-10)6-4-7/h3-6,11H,2,10H2,1H3

Upstream product

• 64-17-5 ethanol 
• 619-67-0 4-Hydrazinobenzoic acid 
• 93-89-0 benzoic acid ethyl ester 
• 40566-85-6 4-ethoxycarbonylphenylhydrazine hydrochloride 
• 94-09-7 p-aminoethylbenzoate 

Downstream Products

• 40431-45-6 2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid ; hydrochloride 
• 4969-98-6 4-[(1,1-dioxo-1λ⁶-thiepan-4-ylidene)-hydrazino]-benzoic acid ethyl ester 
• 285995-20-2 N-[(piperidin-1-yl)amino]ethylbenzoate 
• 73726-32-6 3-(4-Ethoxycarbonyl-phenyl)-5,7-dimethyl-4-oxo-3,4-dihydro-phthalazine-6-carboxylic acid ethyl ester 
• 101094-06-8 ethyl 4-(phenylsulfonyl)benzoate 
• 1330540-11-8 C₂₃H₁₇Cl₂NO₃ 
• 201530-41-8 deferasirox 
• 7272-54-0 2-(5-Carboethoxy-1H-indol-3-yl)ethylamine 
• 89593-76-0 C₁₃H₁₀Cl₂N₂O₃ 
• 1415356-11-4 C₂₀H₁₇ClN₂O₅ 
• 201530-79-2 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid ethyl ester 
• 1242144-88-2 (+/-)-4-{1-[4-(ethoxycarbonyl)phenyl]-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl}benzoic acid 
• 74470-87-4 5-ethoxycarbonyl-2,3,3-trimethylindolenine 
• 1208251-53-9 ethyl 4-{5-[2-(2,6,6-trimethylcyclohex-2-en-1-yl)ethenyl]-1H-pyrazol-1-yl}benzoate 

Relevant articles and documents

SUBSTITUTED SULFONYL HYDRAZIDES AS INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY

The present invention relates to substituted sulfonyl hydrazides that have the ability to inhibit lysine biosynthesis via the diaminopimelate pathway in certain organisms. As a result of this activity these compounds can be used in applications where inhibition of lysine biosynthesis is useful applications of this type include the use of the compound as herbicides and/or anti- bacterial agents.

SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN

Disclosed herein are small molecule heterocyclic inhibitors of sepiapterin reductase (SPR), and pro-drugs and pharmaceutically acceptable salts thereof. The Also featured are pharmaceutical compositions of the compounds and uses of these compounds for the treatment or prevention of pain (e.g., inflammatory pain, nociceptive pain, functional pain, and neuropathic pain)

Methods and Compositions for Modulating P300/CBP Activity

The present invention relates to a method for identifying compounds that modulate the activity of p300/CBP. Compounds of the invention are identified by designing or screening for a compound which binds to at least one amino acid residue of the newly identified lysine-CoA inhibitor binding site, L1 loop, electronegative pocket, or electronegative groove of the HAT domain of p300/CBP and testing the compound for its ability to modulate the activity of p300/CBP. Compositions and methods for preventing or treating diseases or disorders associated with p300/CBP are also provided as is a method for producing a semi-synthetic HAT domain.