5-BroMo-2-Methoxy-4-MethylpyriMidine

Base Information

• Chemical Name: 5-BroMo-2-Methoxy-4-MethylpyriMidine
• CAS No.: 38696-23-0
• Molecular Formula: C6H7BrN2O
• Molecular Weight: 203.03658
• Mol file: 38696-23-0.mol

Synonyms:5-BroMo-2-Methoxy-4-MethylpyriMidine

Chemical Property of 5-BroMo-2-Methoxy-4-MethylpyriMidine

Chemical Property:

• Boiling Point: 277.0±32.0 °C(Predicted)
• PKA: 0.27±0.29(Predicted)
• PSA: 35.01000
• Density: 1.534±0.06 g/cm3(Predicted)
• LogP: 1.55610
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-methoxy-4-methylpyrimidine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-BroMo-2-Methoxy-4-MethylpyriMidine

There total 4 articles about 5-BroMo-2-Methoxy-4-MethylpyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.1%

methanol (67-56-1) + 5-bromo-2-chloro-4-methyl-pyrimidine (633328-95-7) → 5-bromo-2-methoxy-4-methylpyrimidine (38696-23-0)

Guidance literature:

methanol; With sodium; at 25 ℃; for 0.5h;

5-bromo-2-chloro-4-methyl-pyrimidine; at 25 ℃; for 2h;

Reference yield: 51.1%

5-bromo-2-chloro-4-methyl-pyrimidine (633328-95-7) + sodium methylate (124-41-4) → 5-bromo-2-methoxy-4-methylpyrimidine (38696-23-0)

Guidance literature:

sodium methylate; at 25 ℃; for 0.5h;

5-bromo-2-chloro-4-methyl-pyrimidine; at 25 ℃; for 2h;

Reference yield:

methanol (67-56-1) + 5-bromo-2-chloro-4-methyl-pyrimidine (633328-95-7) + sodium methylate (124-41-4) → 5-bromo-2-methoxy-4-methylpyrimidine (38696-23-0)

Guidance literature:

at 25 ℃; for 2h;

upstream raw materials:

5-bromo-2-chloro-4-methyl-pyrimidine

sodium methylate

methanol