1S,2S-bis[(1S)-1-phenylethyl]-1,2-diphenyl-1,2-EthanediaMine

Base Information

• Chemical Name: 1S,2S-bis[(1S)-1-phenylethyl]-1,2-diphenyl-1,2-EthanediaMine
• CAS No.: 314249-68-8
• Molecular Formula: C30H32N2
• Molecular Weight: 420.58848
• Mol file: 314249-68-8.mol

Synonyms:1S,2S-bis[(1S)-1-phenylethyl]-1,2-diphenyl-1,2-EthanediaMine

Chemical Property of 1S,2S-bis[(1S)-1-phenylethyl]-1,2-diphenyl-1,2-EthanediaMine

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

>95%,>98%e.e. ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1S,2S-bis[(1S)-1-phenylethyl]-1,2-diphenyl-1,2-EthanediaMine

There total 21 articles about 1S,2S-bis[(1S)-1-phenylethyl]-1,2-diphenyl-1,2-EthanediaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(E)-N-benzylidene-α-methylbenzylamine (98393-39-6) → N-benzyl-1-phenylethylamine (3193-62-2,17480-69-2,19302-20-6,38235-77-7) + 1,2-diphenyl-N,N'-bis-(1-phenyl-ethyl)-ethane-1,2-diamine (314249-68-8)

Guidance literature:

With sodium hydroxide; zinc; In water; for 7.2h; Ambient temperature;

DOI:10.1016/S0040-4039(98)01904-2

Reference yield: 55.0%

phenyllithium (591-51-5) + (4R,5R)-N,N'-bis[(1S)-1-phenylethyl]-3,6-divinyl-1,7-octadiene-4,5-diamine (280142-38-3) → 1(R),2(R)-di-[(S)-1-phenylethylamino]-1,2-diphenylethane (205988-38-1,314249-68-8)

Guidance literature:

In tetrahydrofuran; -78 degC, 1 h then allowed to come to 20 degC over 2 h;

DOI:10.1002/1099-0690(200108)2001:15<2917::AID-EJOC2917>3.0.CO;2-X

Reference yield: 53.0%

(R)-1-phenylethyl(benzylidene)amine (56941-77-6) → (1'R,1''R)-N,N'-di(α-phenylethyl)-1,2-diphenyl-1,2-ethylenediamine (314249-68-8)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at 65 ℃; for 15h;

DOI:10.1016/S0957-4166(02)00748-6

upstream raw materials:

phenylmagnesium chloride

N,N'-bis<(R)-1-phenylethyl>-1,2-ethanediimine

(R)-1-phenylethyl(benzylidene)amine

(R)-1-phenyl-ethyl-amine