98393-39-6

Basic information

• Product Name: (E)-N-benzylidene-α-methylbenzylamine
• Synonyms: (E)-N-benzylidene-α-methylbenzylamine
• CAS NO: 98393-39-6
• Molecular Weight: 209.291
• Mol File: 98393-39-6.mol
• Article Data: 84

Chemical Properties

• CAS DataBase Reference: (E)-N-benzylidene-α-methylbenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-benzylidene-α-methylbenzylamine(98393-39-6)
• EPA Substance Registry System: (E)-N-benzylidene-α-methylbenzylamine(98393-39-6)

Safety Data

• Hazardous Substances Data: 98393-39-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 618-36-0 rac-methylbenzylamine 
• 14428-98-9 N-benzyl-N-(1-phenylethylidene)amine 
• 100-51-6 benzyl alcohol 
• 74-88-4 methyl iodide 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 128593-66-8 (R)-N-benzyl-(α-methyl-benzyl)amine hydrochloride 
• 3886-69-9 (+)-1-phenylethylamine 
• 100-46-9 benzylamine 
• 780-25-6 N-benzylidene benzylamine 
• 538-51-2 benzylidene phenylamine 
• 3287-99-8 benzylamine hydrochloride 
• 3480-59-9 N-(1-phenylethyl)benzamide 

Downstream Products

• 14428-98-9 N-benzyl-N-(1-phenylethylidene)amine 
• 3193-62-2 (+)-N-benzyl-α-methylbenzylamine 
• 78075-71-5 (4R,αS)-N(1)-(α-methylbenzyl)-4-phenylazetidin-2-one 
• 78075-70-4 N-[(S)-α-methylbenzyl]-4(S)-phenylazetidin-2-one 
• 107909-60-4 N-(α-Adamant-1-ylbenzyl)-α-phenylethylamin 
• 107909-60-4 N-(α-Adamant-1-ylbenzyl)-α-phenylethylamin 
• 135738-67-9 [Phenyl-((S)-1-phenyl-ethylamino)-methyl]-phosphonic acid diisobutyl ester 
• 135738-66-8 [Phenyl-((S)-1-phenyl-ethylamino)-methyl]-phosphonic acid dibutyl ester 
• 89617-49-2 N-((S)-α-Phenylethyl)-3(S)-methyl-4(R)-trans-phenylazetidin-2-one 
• 89617-51-6 N-((S)-α-Phenylethyl)-3(R)-methyl-4(R)-cis-phenylazetidin-2-one 
• 89617-50-5 N-((S)-α-Phenylethyl)-3(S)-methyl-4(S)-cis-phenylazetidin-2-one 
• 89578-33-6 N-((S)-α-Phenylethyl)-3(R)-methyl-4(S)-trans-phenylazetidin-2-one 
• 83171-64-6 [Phenyl-((S)-1-phenyl-ethylamino)-methyl]-phosphonic acid diisopropyl ester 
• 78075-72-6 N-((S)-α-Phenylethyl)-3,3-dimethyl-4(S)-phenylazetidin-2-one 

Relevant articles and documents

Homologation of α-aryl amino acids through quinone-catalyzed decarboxylation/Mukaiyama-Mannich addition

A new method for amino acid homologation by way of formal C-C bond functionalization is reported. This method utilizes a 2-step/1-pot protocol to convert α-amino acids to their corresponding N-protected β-amino esters through quinone-catalyzed oxidative decarboxylation/in situ Mukaiyama-Mannich addition. The scope and limitations of this chemistry are presented. This methodology provides an alternative to the classical Arndt-Eistert homologation for accessing β-amino acid derivatives. The resulting N-protected amine products can be easily deprotected to afford the corresponding free amines.

Synthesis of limonene β-amino alcohol from (R)-(+)-α-methylbenzylamine and (+)-limonene 1,2-epoxide

Two new compounds of β-amino alcohol are obtained using (R) - (+) - α-methylbenzylamine as starting material which is converted into two amines. Each of these compounds reacted in excess with a 1: 1 mixture of cis and trans-limonene oxide in the presence of water as a catalyst. The products obtained show that β-amino alcohol derived from trans-limonene oxide is obtained and unreacted cis-limonene oxide from the reaction mixture as well as the amine is attained. Whereas the addition of the synthesized carbamate of the same primary amine over the 1: 1 mixture of cis and trans -limonene oxide in the presence of water results in the hydrolysis product and the recovery of unreacted trans-limonene oxide.

Manganese-Catalyzed Selective Hydrogenative Cross-Coupling of Nitriles and Amines to Form Secondary Imines

Manganese complexes with tridentate PNN ligands have been synthesized as catalysts for hydrogenative cross-coupling reaction of nitriles and amines to form secondary imines. This reaction afforded a variety of unsymmetrical secondary imines in good yields with excellent selectivity. Investigation of catalyst intermediates indicated that an amido manganese complex may be the active catalyst species for this reaction. (Figure presented.).