1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester

Base Information

Chemical Name:1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester
CAS No.:950271-98-4
Molecular Formula:C11H10ClN3O2
Molecular Weight:251.672
Hs Code.:
Mol file:950271-98-4.mol

Synonyms:1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester;ethyl 1-(3-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate

Suppliers and Price of 1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylicacidethylester 96%
100mg
$ 260.00

Total 3 raw suppliers

Chemical Property of 1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester

Chemical Property:

PSA：57.01000
LogP:2.09740

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylicacidethylester 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester is used as a reactant in the preparation of 1,5- and 1,4-disubstituted 1,2,3-triazoles.

Technology Process of 1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester

There total 3 articles about 1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 108-42-9
3-chloro-aniline

: 623-47-2
propynoic acid ethyl ester

: 950271-98-4
ethyl 1-(3-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate

Guidance literature:: 3-chloro-aniline; propynoic acid ethyl ester; With piperazine; toluene-4-sulfonic acid hydrazide; In acetonitrile; at 20 ℃; for 2h;

With 4-toluenesulfonyl azide; sodium t-butanolate; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1002/cctc.201801366

Reference yield:

: 3296-06-8
1-azido-3-chlorobenzene

: 623-47-2
propynoic acid ethyl ester

: 950271-98-4
ethyl 1-(3-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate

Guidance literature:: With sodium carbonate; L-proline; In dimethyl sulfoxide; at 75 ℃; Microwave irradiation;

Reference yield:

: 108-42-9
3-chloro-aniline

: 950271-98-4
ethyl 1-(3-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium nitrite; trifluoroacetic acid; sodium azide / water / Cooling

2: L-proline; sodium carbonate / dimethyl sulfoxide / 75 °C / Microwave irradiation

With sodium azide; sodium carbonate; trifluoroacetic acid; L-proline; sodium nitrite; In water; dimethyl sulfoxide;