Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans-

Base Information

Chemical Name:Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans-
CAS No.:1166831-68-0
Molecular Formula:C22H27N3O3
Molecular Weight:381.475
Hs Code.:
Mol file:1166831-68-0.mol

Synonyms:Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans-

Suppliers and Price of Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
trans-4-[4-[6-(Aminocarbonyl)-3,5-dimethyl-2-pyrazinyl]phenyl]cyclohexaneaceticAcidMethylEster
10mg
$ 330.00

Chemenu
trans-4-[4-[6-(Aminocarbonyl)-3,5-dimethyl-2-pyrazinyl]phenyl]cyclohexaneaceticacidmethylester 95%+
100mg
$ 1658.00

Total 5 raw suppliers

Chemical Property of Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans-

Chemical Property:

PSA：95.17000
LogP:4.39650

Purity/Quality:

NLT 98% ^*data from raw suppliers

trans-4-[4-[6-(Aminocarbonyl)-3,5-dimethyl-2-pyrazinyl]phenyl]cyclohexaneaceticAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans-

There total 5 articles about Cyclohexaneacetic acid, 4-[4-[6-(aMinocarbonyl)-3,5-diMethyl-2-pyrazinyl]phenyl]-, Methyl ester, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1166828-19-8
6-chloro-3,5-dimethylpyrazine-2-carboxamide

: 701232-69-1
methyl 2-((trans)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclohexyl)acetate

: 1166831-68-0
methyl 2-((1s,4s)-4-(4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl)cyclohexyl)acetate

Guidance literature:: With potassium phosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; ethanol; water; at 80 ℃; for 16h;

Reference yield:

: 1166827-50-4
ethyl 2-{[N-(tert-butoxycarbonyl)-L-alanyl]amino}-3-oxobutanoate

: 1166831-68-0
methyl 2-((1s,4s)-4-(4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl)cyclohexyl)acetate

Guidance literature:: Multi-step reaction with 4 steps

1: trifluoroacetic acid / 1,2-dichloro-ethane / 4 h / Heating

2: trichlorophosphate / propyl cyanide / 0.17 h / 150 °C / Microwave irradiation

3: ammonia / methanol / 20 °C

4: potassium phosphate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; ethanol; water / 16 h / 80 °C

With potassium phosphate; ammonia; trifluoroacetic acid; trichlorophosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In methanol; 1,2-dimethoxyethane; propyl cyanide; ethanol; water; 1,2-dichloro-ethane;

Reference yield:

: 1166827-49-1
ethyl 3,5-dimethyl-6-oxo-1,6-dihydropyrazine-2-carboxylate

: 1166831-68-0
methyl 2-((1s,4s)-4-(4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl)cyclohexyl)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate / propyl cyanide / 0.17 h / 150 °C / Microwave irradiation

2: ammonia / methanol / 20 °C

3: potassium phosphate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; ethanol; water / 16 h / 80 °C

With potassium phosphate; ammonia; trichlorophosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In methanol; 1,2-dimethoxyethane; propyl cyanide; ethanol; water;