2-[(3-Phenylpropyl)amino]ethanethiol

Base Information

• Chemical Name: 2-[(3-Phenylpropyl)amino]ethanethiol
• CAS No.: 7081-80-3
• Molecular Formula: C11H17NS
• Molecular Weight: 195.3244
• Mol file: 7081-80-3.mol

Synonyms:Ethanethiol,2-((3-phenylpropyl)amino);2-((3-Phenylpropyl)amino)ethanethiol;2-(3-Phenyl-propylamino)-ethanthiol;

Chemical Property of 2-[(3-Phenylpropyl)amino]ethanethiol

Chemical Property:

• Vapor Pressure: 0.00104mmHg at 25°C
• Boiling Point: 301.6°Cat760mmHg
• Flash Point: 136.2°C
• PSA: 50.83000
• Density: 1.003g/cm³
• LogP: 2.52950

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(3-Phenylpropyl)amino]ethanethiol

There total 3 articles about 2-[(3-Phenylpropyl)amino]ethanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

thirane (420-12-2) + 3-Phenylpropan-1-amine (2038-57-5) → 2-(3-Phenyl-propylamino)-ethanthiol (7081-80-3)

Guidance literature:

In benzene; at 100 ℃; for 2h;

Reference yield:

ethyl 2-mercaptoethyl carbonate (5628-96-6) + 3-Phenylpropan-1-amine (2038-57-5) → 2-(3-Phenyl-propylamino)-ethanthiol (7081-80-3)

Guidance literature:

In toluene; Heating;

DOI:10.1021/jm00310a028

Reference yield:

2-methyl-4,5-dihydro-thiazole (2346-00-1) + 3-phenylpropyl 4-methylbenzenesulfonate (3742-75-4) → 2-(3-Phenyl-propylamino)-ethanthiol (7081-80-3)

Guidance literature:

Multistep reaction; (i) PhCl, (ii) aq. NaOH, (iii) aq. HCl, AcOH;

DOI:10.1021/jm00321a029

upstream raw materials:

2-methyl-4,5-dihydro-thiazole

3-phenylpropyl 4-methylbenzenesulfonate

ethyl 2-mercaptoethyl carbonate

3-Phenylpropan-1-amine